189084-62-6

Basic information

• Product Name: 2,3',4',6-TETRABROMODIPHENYL ETHER
• Synonyms: PBDE 71;BDE NO 71;2,3',4',6-TETRABDE;2,3',4',6-TETRABROMODIPHENYL ETHER;bde no 71solution;2,3μ,4μ,6-TetraBDE, 2,3μ,4μ,6-Tetrabromodiphenyl ether solution, PBDE 71;(2,6-Dibromophenyl)(3,4-dibromophenyl) ether;2,6-Dibromophenyl 3,4-dibromophenyl ether
• CAS NO: 189084-62-6
• Molecular Formula: C12H6Br4O
• Molecular Weight: 485.79
• EINECS: 208-759-1
• Mol File: 189084-62-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 402.223 °C at 760 mmHg
• Flash Point: -12 °C
• Appearance: /
• Density: 2.161 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,3',4',6-TETRABROMODIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3',4',6-TETRABROMODIPHENYL ETHER(189084-62-6)
• EPA Substance Registry System: 2,3',4',6-TETRABROMODIPHENYL ETHER(189084-62-6)

Safety Data

• Hazard Codes: F,Xn,N
• Statements: 11-38-50/53-65-67
• Safety Statements: 60-61-62-33-29-16-9
• RIDADR: UN 1262 3/PG 2
• WGK Germany: 2
• Hazardous Substances Data: 189084-62-6(Hazardous Substances Data)

Usage

Description

2,3',4',6-TETRABROMODIPHENYL ETHER, also known as a polybrominated diphenyl ether (PBDE), is an organobromine compound characterized by its flame retardant properties. It is a derivative of the broader class of polybrominated diphenyl ethers, which are widely used in various industries due to their ability to inhibit combustion.

Uses

Used in Consumer Product Industry:
2,3',4',6-TETRABROMODIPHENYL ETHER is used as an additive flame retardant for enhancing the fire resistance of various consumer products, such as electronics, textiles, and plastics. Its application helps to slow down the spread of fire, providing additional safety to users and reducing the risk of火灾 (fire-related incidents).
Additionally, as a related compound of PBDE 37, 2,3',4',6-TETRABROMODIPHENYL ETHER may also contribute to environmental pollution concerns, similar to PBDE 37, which is known to potentially lead to pregnancy failure. This highlights the need for careful consideration of the environmental and health implications when using such compounds in industrial applications.

Upstream product

• 608-33-3 2,6-dibromophenol 

Relevant articles and documents

Synthesis of polybrominated diphenyl ethers and their capacity to induce CYP1A by the Ah receptor mediated pathway

Polybrominated diphenyl ethers (PBDEs) have become widely distributed as environmental contaminants due to their use as flame retardants. Their structural similarity to other halogenated aromatic pollutants has led to speculation that they might share toxicological properties such as hepatic enzyme induction. In this work we synthesized a number of PBDE congeners, studied their affinity for rat hepatic Ah receptor through competitive binding assays, and determined their ability to induce hepatic cytochrome P-450 enzymes by means of EROD (ethoxyre-sorufin-O-deethylase) assays in human, rat, chick, and rainbow trout cells. Both pure PBDE congeners and commercial PBDE mixtures had Ah receptor binding affinities 10-2-10-5 times that of 2,3,7,8-tetrachlorodibenzo-p-dioxin. In contrast with polychlorinated biphenyls, Ah receptor binding affinities of PBDEs could not be related to the planarity of the molecule, possibly because the large size of the bromine atoms expands the Ah receptor's binding site. EROD activities of the PBDE congeners followed a similar rank order in all cells. Some congeners, notably PBDE 85, did not follow the usual trend in which strength of Ah receptor binding affinity paralleled P-450 induction potency. Use of the gel retardation assay with a synthetic oligonucleotide indicated that in these cases the liganded Ah receptor failed to bind to the DNA recognition sequence.