189157-31-1Relevant articles and documents
Synthesis and antibacterial activity of 4″ or 6″-alkanoylamino derivatives of arbekacin
Sasaki, Kazushige,Kobayashi, Yoshihiko,Kurihara, Takashi,Yamashita, Yohei,Takahashi, Yoshiaki,Miyake, Toshiaki,Akamatsu, Yuzuru
, p. 741 - 747 (2015)
Arbekacin, an aminoglycoside antibiotic, is an important drug because it shows a potent efficacy against methicillin-resistant Staphylococcus aureus. However, resistance to arbekacin, which is caused mainly by the bifunctional aminoglycoside-modifying enz
NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS (MRSA)
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Page/Page column 51, (2010/11/24)
Disclosed are compounds represented by general formula (I) or pharmacologically acceptable salts or solvates thereof having excellent antimicrobial activity against bacteria causative of severe infections such as pneumonia and septicemia, particularly against MRSA, and also antimicrobial agents comprising these compounds, and pharmaceutical compositions comprising these compounds as an active component.