18916-11-5

Basic information

• Product Name: Benzene, 1-methyl-2-[(2E)-3-phenyl-2-propenyl]-
• CAS NO: 18916-11-5
• Molecular Formula: C16H16
• Molecular Weight: 208.303
• Mol File: 18916-11-5.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methyl-2-[(2E)-3-phenyl-2-propenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methyl-2-[(2E)-3-phenyl-2-propenyl]-(18916-11-5)
• EPA Substance Registry System: Benzene, 1-methyl-2-[(2E)-3-phenyl-2-propenyl]-(18916-11-5)

Safety Data

• Hazardous Substances Data: 18916-11-5(Hazardous Substances Data)

Upstream product

• 83135-71-1 1-acetoxy-1-phenyl-3-o-tolylpropane 
• 87802-71-9 (E)-methyl cinnamyl carbonate 
• 108-88-3 toluene 
• 160879-62-9 methyl 1-phenylprop-2-enyl carbonate 
• 21040-45-9 Cinnamyl acetate 
• 16419-60-6 2-Methylphenylboronic acid 
• 300-57-2 allylbenzene 
• 95-46-5 2-methylphenyl bromide 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 5153-67-3 nitrostyrene 
• 95-47-6 o-xylene 
• 84109-17-1 2-methylphenylzinc chloride 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 38276-72-1 1-methoxy-4-[[(2E)-3-phenyl-2-propen-1-yl]oxy]benzene 

Downstream Products

• 83135-74-4 cis-1-phenyl-3-o-tolylpropene 
• 83135-54-0 (E)-1-methyl-2-(3-phenylprop-1-en-1-yl)benzene 

Relevant articles and documents

Cross-coupling reaction of allylic ethers with aryl Grignard reagents catalyzed by a nickel pincer complex

A cross-coupling reaction of allylic aryl ethers with arylmagnesium reagents was investigated using β-aminoketonato- and β-diketiminato-based pincer-type nickel(II) complexes as catalysts. An β-aminoketonato nickel(II) complex bearing a diphenylphosphino group as a third donor effectively catalyzed the reaction to afford the target cross-coupled products, allylbenzene derivatives, in high yield. The regioselective reaction of a variety of substituted cinnamyl ethers proceeded to give the corresponding linear products. In contrast, α- and γ-alkyl substituted allylic ethers afforded a mixture of the linear and branched products. These results indicated that the coupling reaction proceeded via a π-allyl nickel intermediate.

Nickel-Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents

The direct coupling of allylic alcohols with arylboronic acids or their derivatives catalyzed by Ni(cod)2 in the presence of a catalytic amount of base has been developed. A wide variety of allylic substrates or arylboronic acids turned out to be applicable to this catalytic system. The present method does not require the use of ligands for stabilizing the nickel catalyst in most cases or additional activators for activation of allylic alcohols.

Copper-Catalyzed Alkenylation of Alcohols with β-Nitrostyrenes via a Radical Addition-Elimination Process

A new method for the preparation of allylic alcohol derivatives has been developed via a radical mechanism using DTBP as the radical initiator promoted by copper salt. The C(sp3)-H bond in various alcohols, toluene derivatives, and alkanes were successfully converted into C-C bonds to yield the desired products in moderate to good yields.