189203-98-3

Basic information

• Product Name: Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-
• CAS NO: 189203-98-3
• Molecular Formula: C26H22N3PS
• Molecular Weight: 439.521
• Mol File: 189203-98-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-(189203-98-3)
• EPA Substance Registry System: Hydrazinecarbothioamide, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl-(189203-98-3)

Safety Data

• Hazardous Substances Data: 189203-98-3(Hazardous Substances Data)

Usage

General Description

Hydrazinecarbothioamide and 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl- are two different chemicals. Hydrazinecarbothioamide is an organic compound with the molecular formula CH6N4S, and is commonly used in the pharmaceutical industry as a precursor in the synthesis of various pharmaceutical drugs. It is also used in the production of agricultural chemicals. On the other hand, 2-[[2-(diphenylphosphino)phenyl]methylene]-N-phenyl- is an organophosphorus compound with potential medicinal properties. It is known for its applications in catalysis and as a ligand in transition metal complexes. Both chemicals have distinct properties and applications in different fields, with potential uses in pharmaceuticals, agriculture, and chemical synthesis.

Upstream product

• 50777-76-9 (2-formylphenyl)(diphenyl)phosphine 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 

Downstream Products

• 1610920-62-1 [RuCl(CO)(AsPh₃)(PNS-Ph)] 
• 1610920-59-6 [RuCl(CO)(PPh₃)(PNS-Ph)] 

Relevant articles and documents

the Golden Method : Electrochemical Synthesis Is an Efficient Route to Gold Complexes

Gold compounds to be obtained by the direct electrochemical oxidation of a noble metal are reported. This achievement provides an alternative procedure to obtaining neutral gold compounds with potential medical or catalytic applications.

Efficient and versatile catalysis of N-alkylation of heterocyclic amines with alcohols and one-pot synthesis of 2-aryl substituted benzazoles with newly designed ruthenium(ii) complexes of PNS thiosemicarbazones

Ruthenium(ii) carbonyl complexes with phosphine-functionalized PNS type thiosemicarbazone ligands [RuCl(CO)(EPh3)(L)] (1-6) (E = P or As, L = 2-(2-(diphenylphosphino)benzylidene) thiosemicarbazone (PNS-H), 2-(2-(diphenylphosphino)benzylidene)-N-methylthiosemicarbazone (PNS-Me), 2-(2-(diphenylphosphino)benzylidene)-N-phenylthiosemicarbazone (PNS-Ph)) have been synthesized and characterized by elemental analysis and spectroscopy (IR, UV-Vis, 1H, 13C, 31P-NMR) as well as ESI mass spectrometry. The molecular structures of complexes 1, 2 and 6 were identified by means of single-crystal X-ray diffraction analysis. The analysis revealed that all the complexes possess a distorted octahedral geometry with the ligand coordinating in a uni-negative tridentate PNS fashion. All the ruthenium complexes (1-6) were tested as catalyst for N-alkylation of heteroaromatic amines with alcohols. Notably, complex 2 was found to be a very efficient and versatile catalyst towards N-alkylation of a wide range of heterocyclic amines with alcohols. Complex 2 can also catalyze the direct amination of 2-nitropyridine with benzyl alcohol to the corresponding secondary amine. Furthermore, a preliminary examination of performance for N,N-dialkylation of diamine showed promising results, giving good conversion and high selectivity. In addition, N-alkylation of ortho-substituted anilines (-NH2, -OH and -SH) led to the one-pot synthesis of 2-aryl substituted benzimidazoles, benzoxazoles and benzothiazoles, also revealing the catalytic activity of complex 2. This journal is the Partner Organisations 2014.