189244-67-5

Basic information

• Product Name: 2-Propanol, 1-amino-3-(3-methylphenoxy)-, (2S)-
• CAS NO: 189244-67-5
• Molecular Formula: C10H15NO2
• Molecular Weight: 181.235
• Mol File: 189244-67-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-amino-3-(3-methylphenoxy)-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-amino-3-(3-methylphenoxy)-, (2S)-(189244-67-5)
• EPA Substance Registry System: 2-Propanol, 1-amino-3-(3-methylphenoxy)-, (2S)-(189244-67-5)

Safety Data

• Hazardous Substances Data: 189244-67-5(Hazardous Substances Data)

Upstream product

• 108-39-4 3-methyl-phenol 
• 1415419-08-7 (S)-1-nitro-3-(m-tolyloxy)propan-2-ol 
• 1758-10-7 1-allyloxy-3-methylbenzene 
• 106985-61-9 3-methylphenoxyacetaldehyde cyanohydrin acetate 
• 123048-95-3 3-methylphenoxyacetaldehyde cyanohydrin 
• 176851-48-2 2-(3-methylphenoxy)acetaldehyde 
• 621-24-9 3-m-Tolyloxy-propane-1,2-diol 
• 113080-09-4 Acetic acid (S)-1-cyano-2-m-tolyloxy-ethyl ester 

Downstream Products

• 4198-87-2 (2S)-1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol 

Relevant articles and documents

A new catalyst for the asymmetric Henry reaction: Synthesis of β-nitroethanols in high enantiomeric excess

A new chiral tetrahydrosalen ligand has been designed and synthesized from cis-2,5-diaminobicyclo[2.2.2]octane. The complex generated in situ by the interaction of the ligand with (CuOTf)2·C6H 5CH3 was an efficient catalyst for the asymmetric Henry reaction, producing nitroaldol products in high yield and good stereoselectivity. Henry reactions catalyzed by this tetrahydrosalen-Cu(I) complex led to syntheses of β-adrenergic blocking agents (S)-toliprolol, (S)-moprolol, and (S)-propanolol.