189325-51-7Relevant articles and documents
Thiourea and thiosemicarbazide derivatives: Structure, transformations, and pharmacological activity. Part II. Antihypoxic activity of 1,2,4-triazino[5,6-b]indole derivatives
Tomchin,Uryupov,Zhukova,Kuznetsova,Kostycheva,Smirnov
, p. 125 - 133 (1997)
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Microwave irradiation for accelerating each step for the synthesis of 1,2,4-triazino[5,6-b]indole-3-thiolsand their derivatives from isatin and 5-chloroisatin
El Ashry, El Sayed H.,Ramadan, El Sayed,Abdel Hamid, Hamida M.,Hagar, Mohamed
, p. 723 - 725 (2007/10/03)
Microwave irradiation has been used to accelerate the conversion of isatin (1), 5-chloroisatin (2), and N-benzylisatin (3) to their thiosemicarbazones and their subsequent cyclization into 1,2,4-triazino[5,6-e]indole-3-thiols 7 and 8; and the W-benzyl derivative 9. Selective and complete alkylation of 1, 7, 8, and 9 has also been achieved under microwave irradiation.