1896-61-3

Basic information

• Product Name: (Methyl)tri-4-tolylphosphonium Iodide-d3,13C
• Synonyms: (Methyl)tri-4-tolylphosphonium Iodide-d3,13C;(Methyl)tris(4-Methylphenyl)phosphoniuM Iodide-d3,13C;(Methyl)tris(p-tolyl)phosphoniuM Iodide;(Methyl)tris(4-Methylphenyl)phosphoniuM Iodide-d3
• CAS NO: 1896-61-3
• Molecular Formula: C₂₂H₂₄P*I
• Molecular Weight: 450.331676334
• Product Categories: Aromatics;Isotope Labelled Compounds;Wittig Reagents
• Mol File: 1896-61-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: Ether
• CAS DataBase Reference: (Methyl)tri-4-tolylphosphonium Iodide-d3,13C(CAS DataBase Reference)
• NIST Chemistry Reference: (Methyl)tri-4-tolylphosphonium Iodide-d3,13C(1896-61-3)
• EPA Substance Registry System: (Methyl)tri-4-tolylphosphonium Iodide-d3,13C(1896-61-3)

Safety Data

• Hazardous Substances Data: 1896-61-3(Hazardous Substances Data)

Usage

Chemical Properties

White Solid (Powder)

Upstream product

• 1038-95-5 Tri(p-tolyl)phosphine 
• 74-88-4 methyl iodide 

Downstream Products

• 118977-96-1 C₅₆H₉₇NO₁₂Si₂ 
• 133941-75-0 24,33-Bis-(t.butyl-dimethylsilyl)-FK 506 
• 723-45-5 di(4-tolyl)methylphosphine oxide 
• 108-88-3 toluene 

Relevant articles and documents

Rapid synthesis of 11C-labeled FK506 for positron emission tomography

The present study describes a rapid synthesis method for labeled [11C]FK506 for positron emission tomography (PET). A one-pot reaction from [11C]CH3I, involving a Wittig reaction as the key carbon-carbon bond formation was developed. The chemical process was accomplished using a designed, fully automated synthetic apparatus, and an injectable solution of [11C]FK506 was obtained in only 34 min from [11C]CH3I. The decay-corrected radiochemical yield based on [11C]CH3I was 11.9%, and the specific activity was 39.8 GBq/μmol.