189937-21-1

Basic information

• Product Name: N-(2,4-dibromo-6-methylphenyl)acetamide
• Synonyms: N-(2,4-dibromo-6-methylphenyl)acetamide
• CAS NO: 189937-21-1
• Molecular Weight: 306.985
• Mol File: 189937-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2,4-dibromo-6-methylphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,4-dibromo-6-methylphenyl)acetamide(189937-21-1)
• EPA Substance Registry System: N-(2,4-dibromo-6-methylphenyl)acetamide(189937-21-1)

Safety Data

• Hazardous Substances Data: 189937-21-1(Hazardous Substances Data)

Upstream product

• 30273-41-7 2,4-dibromo-6-methylaniline 
• 64-19-7 acetic acid 
• 95-53-4 o-toluidine 
• 24106-05-6 4'-bromo-2'-methylacetanilide 
• 7732-18-5 water 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 50477-28-6 5,7-Dibromid 

Relevant articles and documents

New insights into bromination process: Effective preparation of Ambroxol

Ambroxol used as an expectorant in treating respiratory diseases was effectively prepared with a total yield of 62 %, with o-toluidine as the feedstock via successive procedures of electrophilic bromination, acetylation, radical benzylic bromination, N-alkylation and hydrolysis processes. The addition of aqueous hydrogen peroxide could enhance the utilisation of liquid bromine in the electrophilic bromination of o-toluidine, avoiding the hazardous HBr generated as a by-product. In addition, liquid bromine promoted by MnO2 was used efficiently for the radical benzylic bromination of N-acetyl-N-(2,4-dibromo-6-methylphenyl)acetamide under mild conditions.