18998-48-6

Basic information

• Product Name: 4H-1,2,4-Triazol-4-amine, N-(phenylmethylene)-
• CAS NO: 18998-48-6
• Molecular Formula: C9H8N4
• Molecular Weight: 172.189
• Mol File: 18998-48-6.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4H-1,2,4-Triazol-4-amine, N-(phenylmethylene)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,2,4-Triazol-4-amine, N-(phenylmethylene)-(18998-48-6)
• EPA Substance Registry System: 4H-1,2,4-Triazol-4-amine, N-(phenylmethylene)-(18998-48-6)

Safety Data

• Hazardous Substances Data: 18998-48-6(Hazardous Substances Data)

Upstream product

• 584-13-4 4-amino-1,2,4-triazole 
• 100-52-7 benzaldehyde 

Downstream Products

• 14309-92-3 N-benzyl-4-nitroaniline 
• 1025447-82-8 C₁₁H₁₀N₄OS 
• 21614-62-0 4-(N-benzyl-N-nitrosoamino)-1,2,4-triazole 
• 6111-75-7 4-(benzylamino)-1,2,4-triazole 
• 89969-48-2 1-(4-Nitro-phenyl)-3-phenyl-3-([1,2,4]triazol-4-ylamino)-propan-1-one 
• 89969-47-1 1,3-Diphenyl-3-([1,2,4]triazol-4-ylamino)-propan-1-one 
• 89969-55-1 1,5-Dimethyl-2-phenyl-4-[phenyl-([1,2,4]triazol-4-ylamino)-methyl]-1,2-dihydro-pyrazol-3-one 
• 1216963-24-4 C₁₇H₁₂ClN₅OS 
• 1216963-03-9 C₁₇H₁₃N₅OS 
• 1216963-44-8 C₁₇H₁₁Cl₂N₅OS 

Relevant articles and documents

Synthesis, crystallographic and spectroscopic studies of dimeric Cui complexes with Schiff-base-containing triazole ligands

New CuI complexes of the Schiff-base-containing triazole ligands N-[(E)-(4-chlorophenyl)methylidene]-4H-1,2,4-triazol-4-amine (C1Phtrz) and N-[(E)-phenylmethylidene]-4H-1,2,4-triazol-4-amine (Phtrz) have been synthesised and characterised. Depe

Dinuclear complexes with a triple N1,N2-triazole bridge that exhibit partial spin crossover and weak antiferromagnetic interactions

The reaction of 4-phenylimino-1,2,4-triazole (1) with FeII, CoII, NiII and CuII thiocyanate produces a series of analogous dinuclear compounds of formula [M2 (1)5 (NCS)4] (2-5) as demonstrated by single-crystal X-ray diffraction studies of the FeII (2) and CoII (3) analogues. The magnetic properties of [Fe2(1)5(NCS)4]·xMeOH (x = 3.5-5) reveal a partial and gradual spin crossover (SCO) centred at TSCO = 115 K. This is confirmed by its crystal structure solved at 100, 150 and 250 K, which exhibits a gradual decrease of the Fe-N bond lengths with temperature. However, the bulk hydrated form of 2 that is generated upon exposure to air of crystals is a high-spin compound that exhibits weak antiferromagnetic interaction. The exchange coupling among the FeII S = 2 ions within the dinuclear neutral complex was evaluated as J/kB = -1.33(3) K by using the Heisenberg Hamiltonian H = -2JS1·S2. Similarly, the magnetic properties of the NiII (4) and CuII (5) analogues are dominated by moderate and weak antiferromagnetic interactions evaluated as J/kB = -13.9(3) and -0.30(5) K, respectively. The presence of strong spin-orbit coupling of the individual CoII ions impeded the evaluation of the likely antiferromagnetic interaction that leads to a singlet ground state in 3. The reported structures of 2 and 3 are new additions to a very scarce family of dinuclear complexes bearing a unique triple N1,N2-triazole bridge. Owing to its relevance in the peculiar properties of 1D triazolebased SCO materials, which are widely studied for their various potential applications, a structural analysis of this triple N1,N2-triazole bridge in reported structures of FeII and CoII trinuclear and 1D compounds is provided.

Synthesis and biological activity of 3-[4H-(1,2,4)-triazolyl]-2-aryl-1,3- thiazolidin-4-ones

4-Amino-1,2,4-triazole (1) undergoes facile condensation with aromatic aldehydes to afford the corresponding 4-(arylidene-amino)-4H-[1,2,4]-triazole (2 a-h) in good yields. Cyclocondensation of compounds (2 a-h) with thioglycolic acid yields 3-[4H-(1,2,4)