190064-28-9

Basic information

• Product Name: 5-(3 4-(DIMETHOXY)PHENYL)-1 3-
• Synonyms: 5-(3 4-(DIMETHOXY)PHENYL)-1 3-;Albb-006893;539902_ALDRICH;Oprea1_609340;ST5320178
• CAS NO: 190064-28-9
• Molecular Formula: C₁₄H₁₆O₄
• Molecular Weight: 248.276
• EINECS: 604-604-1
• Product Categories: Chiral Building Blocks;Ketones;Organic Building Blocks
• Mol File: 190064-28-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 166-170 °C(lit.)
• Boiling Point: 411.6 °C at 760 mmHg
• Flash Point: 184.1 °C
• Appearance: /
• Density: 1.173 g/cm³
• Vapor Pressure: 5.52E-07mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: 5-(3 4-(DIMETHOXY)PHENYL)-1 3-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3 4-(DIMETHOXY)PHENYL)-1 3-(190064-28-9)
• EPA Substance Registry System: 5-(3 4-(DIMETHOXY)PHENYL)-1 3-(190064-28-9)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 190064-28-9(Hazardous Substances Data)

Usage

General Description

5-(3,4-(DIMETHOXY)PHENYL)-1,3-dihydro-2H-indol-3-ol, also known as PNU-99,194, is a chemical compound that belongs to the indole class of chemicals. It is a synthetic derivative of serotonin and acts as a selective 5-HT1A receptor agonist. PNU-99,194 has been studied for its potential therapeutic effects in the treatment of a variety of conditions, including anxiety, depression, and cognitive dysfunction. It has also been investigated for its potential role in modulating neurobehavioral responses and has shown promise as a treatment for neurodegenerative disorders. Overall, PNU-99,194 is a promising chemical compound with potential therapeutic applications in the field of mental health and neurology.

InChI:InChI=1/C14H16O4/c1-17-13-4-3-9(7-14(13)18-2)10-5-11(15)8-12(16)6-10/h3-4,7,10H,5-6,8H2,1-2H3

Upstream product

• 50684-28-1 ethyl 2-(3,4-dimethoxyphenyl)-4,6-dioxocyclohexane carboxylate 

Downstream Products

• 1259284-64-4 9-(4-(3,6-bis(3,4-dimethoxyphenyl)-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)phenyl)-2,7-bis(3,4-dimethoxyphenyl)-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8-(2H)-dione 
• 1259284-65-5 9-(3-(3,6-bis(3,4-dimethoxyphenyl)-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-1H-xanthen-9-yl)phenyl)-2,7-bis(3,4-dimethoxyphenyl)-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8-(2H)-dione 
• 1312794-14-1 C₁₄H₁₅BrO₃ 

Relevant articles and documents

Phenylethanolamine compounds useful as beta 3 agonists, process for producing the same, and intermediates in the production of the same

PCT No. PCT/JP96/03097 Sec. 371 Date Apr. 24, 1998 Sec. 102(e) Date Apr. 24, 1998 PCT Filed Oct. 24, 1996 PCT Pub. No. WO97/15549 PCT Pub. Date May 1, 1997The present invention relates to phenylethanolamine compounds represented by general formula [I]: (where R1 represents hydrogen or halogen; R2 represents hydrogen, hydroxy, lower alkoxy, lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups, lower alkoxy substituted with lower alkylaminocarbonyl which may be substituted with lower alkoxy, lower alkoxy substituted with cyclic aminocarbonyl of 4 to 6 carbon atoms, lower alkoxycarbonyl or carboxy; R3 represents hydrogen, hydroxy, lower alkoxy or lower alkoxy substituted with one or two lower alkoxycarbonyl or carboxy groups; R2 and R3 may be bonded to each other to form methylenedioxy substituted with carboxy or lower alkoxycarbonyl; and m and n are 0 or 1), and their pharmacologically acceptable salts, which have a potent beta 3 adrenergic stimulating effect and high beta 3 adrenergic receptor selectivity, as well as to processes for their production and intermediates in their production.