190187-33-8

Basic information

• Product Name: (S)-3-[(1R,2S)-2-Benzyloxycarbonylamino-1-cyano-3-(1H-indol-3-yl)-propylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid benzyl ester
• CAS NO: 190187-33-8
• Molecular Weight: 700.794
• Mol File: 190187-33-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-[(1R,2S)-2-Benzyloxycarbonylamino-1-cyano-3-(1H-indol-3-yl)-propylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-[(1R,2S)-2-Benzyloxycarbonylamino-1-cyano-3-(1H-indol-3-yl)-propylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid benzyl ester(190187-33-8)
• EPA Substance Registry System: (S)-3-[(1R,2S)-2-Benzyloxycarbonylamino-1-cyano-3-(1H-indol-3-yl)-propylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid benzyl ester(190187-33-8)

Safety Data

• Hazardous Substances Data: 190187-33-8(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 5609-55-2 O-benzylaspartyl-phenylalanine amide 
• 139091-30-8 (S)-benzyl (1-(indol-3-yl)-3-oxopropan-2-yl)carbamate 

Downstream Products

• 190187-42-9 (S)-3-[(1R,2S)-2-Amino-1-cyano-3-(1H-indol-3-yl)-propylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid 

Relevant articles and documents

Pseudopeptide CCK-4 analogues incorporating the Ψ[CH(CN)NH] peptide bond surrogate

The synthesis, binding to CCK receptors, and in vitro functional activity of pseudopeptide CCK-4 analogues incorporating the (R) or (S) Ψ[CH(CN)NH] peptide bond surrogate at the Nle31-Asp32 or Trp30-Nle31 bonds are described. Z-TrpΨ[(S)CH(CN)NH]Nle-Asp-Phe-NH2 retained the high CCK-B receptor binding affinity of Boc-[Nle31]-CCK-4, and was a potent and selective CCK-B antagonist in the isolated guinea pig ileum.