1903-75-9 Usage
Description
N-METHYL-4-PIPERIDINECARBOXAMIDE HYDROCHLORIDE is an organic compound that serves as a key intermediate in the synthesis of various nitrogen heterocyclic compounds. It is characterized by its chemical structure, which includes a piperidine ring with a carboxamide group and a methyl group attached to the nitrogen atom. N-METHYL-4-PIPERIDINECARBOXAMIDE HYDROCHLORIDE plays a crucial role in the development of pharmaceuticals targeting specific enzymes.
Uses
Used in Pharmaceutical Industry:
N-METHYL-4-PIPERIDINECARBOXAMIDE HYDROCHLORIDE is used as a building block for the preparation of nitrogen heterocyclic compounds that act as inhibitors of 3'',5''-cyclic nucleotide-specific phosphodiesterase 10 (PDE10). PDE10 is an enzyme that plays a role in the regulation of neurotransmitter signaling in the brain, and its inhibition has been linked to the treatment of various psychiatric and neurological disorders, such as schizophrenia and Huntington's disease. By using N-METHYL-4-PIPERIDINECARBOXAMIDE HYDROCHLORIDE as a starting material, researchers can develop novel PDE10 inhibitors with improved potency, selectivity, and pharmacokinetic properties, potentially leading to more effective treatments for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1903-75-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,0 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1903-75:
(6*1)+(5*9)+(4*0)+(3*3)+(2*7)+(1*5)=79
79 % 10 = 9
So 1903-75-9 is a valid CAS Registry Number.
1903-75-9Relevant articles and documents
SULFONAMIDE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER
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Paragraph 00181, (2021/04/23)
The present disclosure relates generally to a class of sulfonamide-based compounds, compositions containing the same and the therapeutic use of the compounds in the treatment of cancer.
A highly efficient Pd-C catalytic hydrogenation of pyridine nucleus under mild conditions
Cheng, Chuanjie,Xu, Jimin,Zhu, Rui,Xing, Lixin,Wang, Xinyan,Hu, Yuefei
supporting information; experimental part, p. 8538 - 8541 (2009/12/24)
A synergistic Pd-C catalytic hydrogenation of 4-pyridinecarboxamides straightforward to 4-piperidinecarboxamide hydrochlorides was developed in the presence of ClCH2CHCl2. It provided a novel strategy for highly efficient hydrogenati
