1904-24-1

Basic information

• Product Name: 5-AMINO-3-ETHYL-1H-PYRAZOLE
• Synonyms: 5-AMINO-3-ETHYL-1H-PYRAZOLE;5-ETHYL-2H-PYRAZOL-3-YLAMINE;1H-Pyrazol-3-amine, 5-ethyl-;3-AMino-5-ethylpyrazole;5-ethyl-3-aMino-1H-pyrazole;3-Amino-5-ethyl-2H-pyrazole;3-Ethyl-1H-pyrazol-5-amine hydrochloride;H50782
• CAS NO: 1904-24-1
• Molecular Formula: C₅H₉N₃
• Molecular Weight: 111.15
• Mol File: 1904-24-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 313.758 °C at 760 mmHg
• Flash Point: >110℃
• Appearance: /
• Density: 1.126 g/mL at 25 °C
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5420
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 15.84±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-3-ETHYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-3-ETHYL-1H-PYRAZOLE(1904-24-1)
• EPA Substance Registry System: 5-AMINO-3-ETHYL-1H-PYRAZOLE(1904-24-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 23-26-36/37/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 1904-24-1(Hazardous Substances Data)

Usage

Description

5-AMINO-3-ETHYL-1H-PYRAZOLE is an organic compound that serves as a crucial intermediate in various chemical and pharmaceutical applications due to its unique molecular structure and reactivity.

Uses

Used in Organic Synthesis:
5-AMINO-3-ETHYL-1H-PYRAZOLE is used as a key intermediate for the synthesis of various organic compounds. Its presence in the molecular structure allows for further functionalization and the creation of a wide range of products.
Used in Pharmaceutical Industry:
5-AMINO-3-ETHYL-1H-PYRAZOLE is used as a building block in the development of new pharmaceuticals. Its unique chemical properties make it a valuable component in the design and synthesis of novel drugs with potential therapeutic applications.
Used in Agrochemicals:
5-AMINO-3-ETHYL-1H-PYRAZOLE is used as a raw material in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved agricultural outcomes.
Used in Dye Industry:
5-AMINO-3-ETHYL-1H-PYRAZOLE is used as an intermediate in the synthesis of various dyes and pigments. Its chemical properties contribute to the development of dyes with specific color characteristics and improved performance in various applications.

InChI:InChI=1/C5H9N3/c1-2-4-3-5(6)8-7-4/h3H,2H2,1H3,(H3,6,7,8)

Upstream product

• 33279-01-5 3-oxo-pentanenitrile 
• 554-12-1 propanoic acid methyl ester 
• 75-05-8 acetonitrile 

Downstream Products

• 1429171-59-4 4-[3-ethyl-6-(3-fluoro-4-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carbonyl]piperazine-1-carboxylic acid tert-butyl ester 
• 1429171-31-2 3-ethyl-6-(3-fluoro-4-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid 
• 927679-40-1 6-benzyl-2-chloro-N-(5-ethyl-1H-pyrazol-3-yl)pyrimidin-4-amine 
• 948573-56-6 N-(5-ethyl-1H-pyrazol-3-yl)-2-(4-hydroxy-2-methoxyphenyl)acetamide 
• 1440804-91-0 C₂₀H₃₀N₄O₂ 

Relevant articles and documents

Identification of TRD-35 as Potent and Selective DRAK2 Inhibitor

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Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.

Pyrazolotriazines as inhibitors of nucleases

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.