190662-30-7 Usage
Description
(17α)-3,3-[1,2-Ethanediylbis(oxy)]-17-hydroxy-19-norpregna-5(10),9(11)-diene-21-nitrile is a synthetic steroid compound derived from 19-Nortestosterone, characterized by its unique chemical structure featuring a nitrile group at the 21st position and hydroxyl groups at the 3rd and 17th positions. It serves as an intermediate in the synthesis of Dienogest, a hormone used in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
(17α)-3,3-[1,2-Ethanediylbis(oxy)]-17-hydroxy-19-norpregna-5(10),9(11)-diene-21-nitrile is used as an intermediate compound for the production of Dienogest (D441870), which is a derivative of 19-Nortestosterone (N315000). Dienogest is an oral contraceptive that is typically used in combination with estrogen to provide effective birth control.
Application Reason:
The compound's role as an intermediate in the synthesis of Dienogest is significant due to the contraceptive's widespread use and effectiveness in preventing pregnancy when taken in combination with estrogen. Dienogest's mechanism of action involves the inhibition of ovulation, alteration of cervical mucus to impede sperm penetration, and modification of the endometrium to prevent implantation of a fertilized egg.
Check Digit Verification of cas no
The CAS Registry Mumber 190662-30-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,0,6,6 and 2 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 190662-30:
(8*1)+(7*9)+(6*0)+(5*6)+(4*6)+(3*2)+(2*3)+(1*0)=137
137 % 10 = 7
So 190662-30-7 is a valid CAS Registry Number.
190662-30-7Relevant articles and documents
Preparation method of dienogest
-
Paragraph 0079-0082, (2021/01/24)
The invention relates to a preparation method of dienogest. The preparation method comprises the following steps: providing a compound with a structure shown as a formula (II); and carrying out an acidolysis deprotection reaction on the compound shown in the formula (II) in an aqueous fluoboric acid solution to prepare a compound with a structure shown in a formula (I). According to the preparation method of the dienogest, the problems of low purity and dark color of a crude product of an acidolysis deprotection process are fundamentally solved, a production process is greatly simplified, andthe production cost of an enterprise is reduced.
Method for the preparation of steroid derivative ketal
-
, (2008/06/13)
The invention relates to a method for the preparation of a compound of formula II: STR1 wherein a compound of formula V: STR2 is condensed with a compound of the formula CH3 -C(OR4 O)-(CH2)3 -XHal and R1, R2, R3, R4, X and Hal are as defined by the specification.