1908-88-9 Usage
Description
4,4-Dimethylthiazolidine-2-thione is a sulfur-containing heterocyclic compound with the molecular formula C6H11NS. It features a five-membered ring structure and has been identified to have multiple biological activities, such as antibacterial, antifungal, and antioxidant properties. 4,4-dimethylthiazolidine-2-thione is notable for its applications in the synthesis of pharmaceuticals, as a rubber vulcanization accelerator, and for its potential therapeutic uses in diabetes and neurodegenerative diseases, showcasing its versatility in chemistry and medicine.
Uses
Used in Pharmaceutical Synthesis:
4,4-Dimethylthiazolidine-2-thione is utilized as a key intermediate in the synthesis of various pharmaceuticals due to its unique chemical structure and biological activities, contributing to the development of new drugs with potential therapeutic benefits.
Used as a Rubber Vulcanization Accelerator:
In the rubber industry, 4,4-dimethylthiazolidine-2-thione serves as an effective vulcanization accelerator, enhancing the process of rubber cross-linking and improving the material's overall properties, such as strength and elasticity.
Used in Antimicrobial Applications:
Leveraging its antibacterial and antifungal properties, 4,4-dimethylthiazolidine-2-thione is applied as an antimicrobial agent in various settings, including medical and industrial uses, to prevent the growth of harmful microorganisms and maintain cleanliness and safety.
Used in Antioxidant Formulations:
Capitalizing on its antioxidant characteristics, 4,4-dimethylthiazolidine-2-thione is employed in antioxidant formulations to protect against oxidative stress and damage, which is particularly relevant in the cosmetics and food preservation industries.
Used in Diabetes Treatment Research:
4,4-Dimethylthiazolidine-2-thione is explored for its potential role in diabetes treatment, with ongoing research investigating its capacity to manage or alleviate symptoms associated with the condition.
Used in Neurodegenerative Disease Therapy:
4,4-dimethylthiazolidine-2-thione is also under investigation for its possible therapeutic effects in the treatment of neurodegenerative diseases, given its diverse biological activities that may contribute to neuroprotection and symptom management.
Check Digit Verification of cas no
The CAS Registry Mumber 1908-88-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,0 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1908-88:
(6*1)+(5*9)+(4*0)+(3*8)+(2*8)+(1*8)=99
99 % 10 = 9
So 1908-88-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H9NS2/c1-5(2)3-8-4(7)6-5/h3H2,1-2H3,(H,6,7)
1908-88-9Relevant articles and documents
Thorpe-Ingold effect in the reaction of vicinal amino primary alcohol hydrogen sulfates and carbon disulfide
Chen, Ning,Huang, Zhongyan,Zhou, Chan,Xu, Jiaxi
experimental part, p. 7971 - 7976 (2011/11/14)
The Thorpe-Ingold effect is a key factor that affects the ring-closure rates and efficiency, as well as the structure of products in some ring-closure reactions. The reaction of vicinal amino primary alcohol hydrogen sulfates and carbon disulfide in the presence of potassium hydroxide produces the desired 4,4-disubstituted thiazolidine-2-thiones, and their isomers 5,5-disubstituted derivatives companying with their oxygen analogues 4,4-disubstituted oxazolidine-2-thiones. The formation of 5,5-disubstituted thiazolidine-2-thiones was rationalized via 2,2-disubstituted aziridine-1-carbodithioate intermediates, which were generated due to the Thorpe-Ingold effect. 4,4-Disubstituted oxazolidine-2-thiones were generated from carbon disulfide and free amino alcohols yielded via basic hydrolysis of active amino alcohol hydrogen sulfates in the reaction system.
