19109-69-4

Basic information

• Product Name: 1,2-Benzenediacetic acid, dimethyl ester
• Synonyms: dimethyl 1,2-benzenediacetate;(o-Phenylen)bis(essigsaeure-methylester);1,2-Benzenediacetic acid,dimethyl ester;(2-methoxycarbonylmethylphenyl)acetic acid methyl ester;dimethyl o-phenylenediacetate;o-Phenylendi-essigsaeure-dimethylester;dimethyl 2,2'-(1,2-phenylene)diacetate;o-phenylenedi-acetic acid dimethyl ester
• CAS NO: 19109-69-4
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol File: 19109-69-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediacetic acid, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediacetic acid, dimethyl ester(19109-69-4)
• EPA Substance Registry System: 1,2-Benzenediacetic acid, dimethyl ester(19109-69-4)

Safety Data

• Hazardous Substances Data: 19109-69-4(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Odor

Fruity

Uses

a. Fragrance ingredient in perfumes and personal care products
b. Intermediate in the synthesis of organic compounds (pharmaceuticals, polymers, and dyes)

Toxicity

Relatively low

Safety precautions

Handle with care and proper safety measures to avoid skin and eye irritation

Upstream product

• 67-56-1 methanol 
• 7500-53-0 1,2-Phenylenediacetic acid 
• 95-47-6 o-xylene 
• 201230-82-2 carbon monoxide 
• 91-13-4 α,α'-dibromo-o-xylene 

Downstream Products

• 17378-99-3 2,2’-(1,2-phenylene)diethanol 
• 150008-19-8 1,2-bis(2-bromo-2,2-dideuterioethyl)benzene 
• 63969-85-7 <2-(2-Hydroxyethyl)phenyl>essigsaeure-methylester 
• 136863-22-4 <2-(2-Hydroxyethyl)phenyl>essigsaeure 
• 936479-59-3 dibenzyl 2-(2-methoxymethoxyethyl)phenylmalonate 
• 936479-60-6 dibenzyl 2-(2-hydroxyethyl)phenylmalonate 
• 936479-61-7 dibenzyl 2-(2-oxoethyl)phenylmalonate 
• 936479-58-2 benzyl 2-(2-methoxymethoxyethyl)phenylacetate 
• 936479-57-1 benzyl 2-(2-hydroxyethyl)phenylacetate 
• 936479-62-8 2-(2-oxoethyl)phenylmalonic acid 
• 104620-34-0 methyl 2-oxo-2,3-dihydro-1H-indane-1-carboxylate 
• 150008-22-3 1,2-bis(2,2-dideuterio-2-hydroxyethyl)benzene 
• 72686-08-9 <2-(Methoxycarbonylmethyl)phenyl>essigsaeure 

Relevant articles and documents

PHENYLENE OXO-DIESTER PLASTICIZERS AND METHODS OF MAKING

A process for making non-phthalate, 1,2-phenylene oxo-diester plasticizers for polymer compositions, by selectively hydrogenating naphthalene to form a partially hydrogenated naphthalene, oxygenating said partially hydrogenated naphthalene to form phenylene diacids, and esterifying said phenylene diacids with oxo-alcohols to form 1,2-phenylene oxo-diesters. Also a process for making phenylene oxo-diester plasticizers by selectively brominating xylenes to form bisbromomethylbenzene, catalytic carboalkoxylation of the bromo-compound to form phenylene diacetate, followed by transesterification to form the phenylene oxo-diester.

PALLADACYLES, THEIR PREPARATION AND CATALYTIC PROCESSES INVOLVING THEIR USE AS CATALYST, ESPECIALLY CATALYTIC CARBONYLATION PROCESSES

The present invention relates to palladium compounds and their use as catalysts for improved catalytic processes. Specifically there is disclosed an improved catalytic carbonylation process and improved carbonylation catalysts. Catalysts in dimer form are also disclosed, as is their catalytic activity and methods of making the compounds.

Tetrahydrobenzazepines and their use

The invention relates to tetrahydrobenzazepines of the general formula I in which the variables Ar, A, B, Y, R1 and R2 have the meaninigs indicated in claim 1, as well as the N-oxides of these compounds, the physiologically tolerated acid addition salts of these compounds and the physiologically tolerated acid addition salts of the N-oxides. The invention also relates to a pharmaceutical compositon that comprises at least one tetrahydrobenzazepine compound of the formula I, the physically tolerated acid addition salt of I, the N-oxide of compound of the formula I and/or the physically tolerated acid addition salts of the N-oxides of I, and further to the use of a compound according to the present invention for treating disorders that respond benefically to dopamine D3 receptor antagonists or dopamine D3 agonists. The compounds according to the invention are preferably useful for the treatment of disorders of the central nervous system such as schizophrenia and depression and for the treatment of renal function disorders.