1912-47-6

Basic information

• Product Name: 5-METHYLINDOLE-3-ACETIC ACID
• Synonyms: 5-METHYLINDOLE-3-ACETIC ACID;(5-METHYL-1H-INDOL-3-YL)-ACETIC ACID;5-METHYLINDOLE-3-ACETIC ACID 98% (HPLC);5-Me-IAA;2-(5-Methyl-1H-indol-3-yl)acetic acid;5-METHYLINDOLE-3-ACETIC ACID(5MeIAA);5-Methyl Indole-3-acetate Acid;2-(5-methyl-1H-indol-3-yl)ethanoic acid
• CAS NO: 1912-47-6
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.21
• Product Categories: Indoles and derivatives;pharmacetical
• Mol File: 1912-47-6.mol
• Article Data: 7

Chemical Properties

• Melting Point: 151 °C
• Boiling Point: 420.8 °C at 760 mmHg
• Flash Point: 208.3 °C
• Appearance: /
• Density: 1.299 g/cm³
• Storage Temp.: 2-8°C
• PKA: 4.53±0.30(Predicted)
• CAS DataBase Reference: 5-METHYLINDOLE-3-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYLINDOLE-3-ACETIC ACID(1912-47-6)
• EPA Substance Registry System: 5-METHYLINDOLE-3-ACETIC ACID(1912-47-6)

Safety Data

• Hazardous Substances Data: 1912-47-6(Hazardous Substances Data)

Usage

Description

5-METHYLINDOLE-3-ACETIC ACID is a chemical compound derived from Indole-3-acetic acid, which is a well-known plant growth regulator. 5-METHYLINDOLE-3-ACETIC ACID possesses the ability to induce cell division and cell elongation, thereby playing a significant role in promoting plant growth.

Uses

Used in Agricultural Industry:
5-METHYLINDOLE-3-ACETIC ACID is used as a plant growth regulator for enhancing plant growth and development. It stimulates cell division and elongation, leading to improved crop yields and overall plant health.
Used in Plant Biotechnology:
In the field of plant biotechnology, 5-METHYLINDOLE-3-ACETIC ACID is utilized as a tool to study the mechanisms underlying plant growth and development. Understanding its role in cell division and elongation can provide valuable insights into the genetic and molecular processes that govern these essential aspects of plant life.

Upstream product

• 1337870-84-4 (5-methyl-indol-3-yl)-acetic acid methyl ester 
• 65881-14-3 2-(5-methyl-1H-indol-3-yl)acetonitrile 
• 156695-43-1 (5-Methyl-1H-indol-3-yl)-oxo-acetic acid 
• 115956-14-4 2-(5-methyl-1H-indol-3-yl)-2-oxoacetyl chloride 
• 614-96-0 5-methyl-1H-indole 
• 692-29-5 Succinic semialdehyde 
• 539-44-6 N-4-methylphenylhydrazine 

Downstream Products

• 1337870-84-4 (5-methyl-indol-3-yl)-acetic acid methyl ester 
• 924635-02-9 2-(1-(benzyloxycarbonyl)-5-methyl-1H-indol-3-yl)acetic acid 
• 91957-21-0 5-methyl-1H-indole-3-acetic acid ethyl e 
• 39595-23-8 2-(5-methyl-1H-indol-3-yl)ethan-1-ol 
• 1383933-35-4 C₁₈H₁₈N₂O 
• 1383933-36-5 N-benzyl-2-(1,5-dimethyl-1H-indol-3-yl)acetamide 
• 924633-74-9 benzyl 3-(3-acetoxy-2-oxopropyl)-5-methyl-1H-indole-1-carboxylate 
• 924635-03-0 benzyl 3-(3-chloro-2-oxopropyl)-5-methyl-1H-indole-1-carboxylate 
• 442883-72-9 5-methyl-3-methylene-2-oxindole 

Relevant articles and documents

Asymmetric Dearomatizing Fluoroamidation of Indole Derivatives with Dianionic Phase-Transfer Catalyst

Asymmetric dearomatizing fluorocyclization of indole derivatives was investigated using a dicarboxylate phase-transfer catalyst. This reaction proceeds under mild reaction conditions to provide fluoropyrroloindoline derivatives in a highly enantioselective manner. Various substitution patterns on the indole ring are well tolerated. To facilitate the reaction and ensure reproducibility, the addition of water is essential, and its possible role is discussed.

A substituted indole -3 - acetic acid synthesis method (by machine translation)

The present invention provides a substituted indole - 3 - acetic acid synthesis method, comprises the following steps: (1) in order to replace the indole as the starting material, with the acylation reagent under the action of catalyst through the tutor - acylation to obtain the 1, 3 - diacetyl substituted indole; (2) intermediate 1, 3 - diacetyl substituted indole does not need refining, directly with the morpholine and sulfur by the Willgerodt - Kindler rearrangement reaction, the inorganic under the catalysis of alkali hydrolysis, acidified to obtain substituted indole - 3 - acetic acid. (by machine translation)

Compounds exhibiting thrombopoietin-like activities

The compounds of the invention are compounds represented by the following general formula (1): wherein E represents one selected from the group consisting of a methylidyne group and a nitrilo group, R1 represents one selected from the group consisting of optionally substituted aryl groups and optionally substituted heteroaryl groups, R2 represents one selected from the group consisting of a hydrogen atom and alkyl groups, W1 represents an amino acid residue, A represents one selected from the group consisting of a carbonyl group and a sulfonyl group, X1 represents one selected from the group consisting of optionally substituted alkylene groups and optionally substituted alkenylene groups, and p represents 0 or 1; and their pharmacologically acceptable salts, which exhibit thrombopoietin-like activity.