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19152-38-6

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19152-38-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 19152-38-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,1,5 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 19152-38:
(7*1)+(6*9)+(5*1)+(4*5)+(3*2)+(2*3)+(1*8)=106
106 % 10 = 6
So 19152-38-6 is a valid CAS Registry Number.

19152-38-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-3-(4-chlorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

1.2 Other means of identification

Product number -
Other names 4-Chlor-4'-hydroxy-trans-chalkon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:19152-38-6 SDS

19152-38-6Downstream Products

19152-38-6Relevant articles and documents

Synthesis and antidyslipidemic activity of chalcone fibrates

Shukla, Poonam,Srivastava, Swayam P.,Srivastava, Rohit,Rawat, Arun K.,Srivastava, Arvind K.,Pratap, Ram

, p. 3475 - 3478 (2011)

A series of chalcone based PPAR-α agonists were synthesized and evaluated for their antidyslipidemic activity in high fructose high fat fed dyslipidemic Syrian golden hamsters. Most of the compounds exhibited antidyslipidemic activity. The compounds 4c an

Synthesis, characterization, antimicrobial activities, and structural studies of Lanthanide (III) complexes with 1-(4-Chlorophenyl)-3-(4-fluoro/ hydroxyphenyl)prop-2-en-1-thiosemicarbazone

Oza, Chandra K.,Jain, Meenakshi,Jain, Neelima,Verma, Dinesh

, p. 377 - 386 (2010)

Twelve coordinate lanthanide (III) complexes with the general composition [Ln L3Xn(H2O)n] where Ln = Pr(III), Sm(III), Eu (III), Gd (III), Tb (III), Dy (III), X = Cl-1, NO3 -2, n = 2-7, and

Charge transfer based "turn-on" chemosensor for Zn2 + ion recognition using new triaryl pyrazoline derivative

Jeyanthi, Dharmaraj,Iniya, Murugan,Krishnaveni, Karuppiah,Chellappa, Duraisamy

, p. 231 - 237 (2016)

The fluoroionophore PY serves as a selective and fluorimetric chemosensor for Zn2 + based on charge transfer (CT). A mechanism for the binding mode was proposed based on fluorescence changes, NMR experiments and theoretical calculations. The 1:

Synthesis, Crystal Structure, Biological Evaluation, DFT Calculations and Third Order Nonlinear Optical Studies of Pyrazolines

Gaonkar, Santosh L.,Hari, Gangadhar,Lokanath, N. K.,Naraharisetty, Sri Ram G,Nayak, Swarnagowri,Pai, K. S. R.,Parol, Vinay,Sinha, Rajeev K.

, (2021/06/15)

Novel pyrazoline derivatives were synthesized and characterized by FTIR, NMR, UV-visible, and mass spectral studies. All the synthesized compounds 6a-f were screened for anticancer activity against MCF-7 and HCT 116 cell lines via SRB assay. Among the synthesized pyrazolines 6b and 6f showed appreciable anticancer activity. The molecular docking study was done with two proteins (PDB No: 1M17 and 5ZTO) to study the binding interactions of the compounds with proteins. ADME study showed that the compounds exhibited drug-likeness properties, following Lipinski's rule of five. The molecular structure of compound 6b was studied using the single-crystal X-ray diffraction method. The structural, absorption and first static hyperpolarizability properties of the compound 6b were studied using density functional theory (DFT) calculations. The experimental data and calculated FTIR and UV-visible spectral data are in good agreement. The third order nonlinear optical properties were studied using open and closed aperture z-scan techniques. The compound 6b showed nonlinear absorption(β) of 1.94×10?11m/W at intensity (I0) is 4.49GW/cm2. Third order nonlinear susceptibility is of the order of 10?12 esu and this indicates the molecule has the potential to be used in nonlinear optical device applications.

New chalcone derivatives: Synthesis, antiviral activity and mechanism of action

Fu, Yun,Gan, Xiuhai,Hu, Deyu,Liu, Dan,Ren, Xiaoli,Song, Baoan,Zeng, Huanan

, p. 24483 - 24490 (2020/07/15)

In this work, twenty-eight chalcone derivatives containing a purine (sulfur) ether moiety were synthesized and their antiviral activities were evaluated. Biological results showed that compound 5d exhibited outstanding inactive activity against tobacco mosaic virus (TMV) in vivo (EC50 = 65.8 μg mL-1), which is significantly superior to that of ribavirin (EC50 = 154.3 μg mL-1). Transmission electron microscopy indicated that compound 5d can break the integrity of TMV particles. The results of microscale thermophoresis, fluorescence titration and molecular docking showed that compound 5d had stronger combining affinity (Ka = 1.02 ×105 L mol-1, Kd = 13.4 μmol L-1) with TMV coat protein (TMV-CP), which is due to the formation of five hydrogen bonds between compound 5d and the amino-acid residues of TMV-CP. These findings revealed that compound 5d can effectively inhibit the infective ability of TMV. This work provides inspiration and reference for the discovery of new antiviral agents.

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