19170-96-8

Basic information

• Product Name: 2-METHYLPROPANE-D10
• Synonyms: ISOBUTANE (D10);2-METHYLPROPANE-D10;2-Methylpropane-D10 (gas);ISOBUTANE (D10, 98%)
• CAS NO: 19170-96-8
• Molecular Formula: C4D10
• Molecular Weight: 68.18
• Mol File: 19170-96-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: -12 °C(lit.)
• Flash Point: -83 °C
• Appearance: /
• CAS DataBase Reference: 2-METHYLPROPANE-D10(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLPROPANE-D10(19170-96-8)
• EPA Substance Registry System: 2-METHYLPROPANE-D10(19170-96-8)

Safety Data

• Hazard Codes: F+
• Statements: 12
• Safety Statements: 9-16
• RIDADR: UN 1969 2.1
• Hazardous Substances Data: 19170-96-8(Hazardous Substances Data)

Usage

General Description

2-Methylpropane-D10, also known as tert-butyl-d10, is a deuterated form of 2-methylpropane, a colorless, flammable gas widely used as a refrigerant and propellant in aerosol products. The "D10" designation indicates the presence of deuterium, a stable isotope of hydrogen, at 10 of the 12 hydrogen atoms in the molecule. This heavy isotope substitution allows for the tracking of the compound in chemical reactions and experiments using techniques such as nuclear magnetic resonance (NMR) spectroscopy. 2-Methylpropane-D10 has a similar chemical and physical properties to 2-methylpropane but is useful for the study of reaction mechanisms and metabolic pathways due to the isotopic labeling. Additionally, it can be used as an internal standard in mass spectrometry analyses.

Upstream product

• 918-20-7 tert-butyl chloride-d9 
• 75-28-5 Isobutane 
• 13183-68-1 2-methylpropane-2-d1 

Relevant articles and documents

Deuterium Exchange Reactions of Isobutane, n-Hexane, and n-Heptane Catalyzed over Platinum Single Crystal Surfaces

Isotopic exchange reactions of isobutane, n-heptane, and n-hexane with deuterium gas have been investigated near atmospheric pressure in the temperature range 500-650 K over the flat (111) and kinked (10,8,7) crystal faces of platinum.The exchange kinetics at low conversion displayed zero activation energy, a first-order dependence on D2 pressure, and a strong negative-order dependence on the surface coverage by strongly bound carbonaceous species.Initial exchange rates and product distributions were not influenced appreciably by the presence of steps and kinks on the platinum surface, and the exchange product distributions varied little with temperature, D2 pressure, and surface composition.Hydrocarbon (HC) conversion and deuterium exchange rates measured simultaneously for n-hexane reactions catalyzed over Pt(111) revealed that deuterium exchange always occurs more rapidly as compared to all other competing chemical reactions.

Synthesis of deuterium labeled isobutane: Isobutane-2-d1, isobutane-1-d9 and isobutane-d10

2-Methylpropane-2-d1 (isobutane-2-d1), 2-(methyl-d3)-propane-1,1,1,3,3,3-d6 (nonadeuterated isobutane) and 2-methylpropane-d10 (perdeuterated isobutane) were synthesized by using a combination of classical organic chemistry and recently developed H/D exchange processes on solid acids. Isobutane-2-d1 was synthesized from t-butyl chloride by Grignard synthesis with an overall yield of 27.0% (chemical purity: 99.9% and isotopic purity: 96.0%). Isobutane-1-d9 was prepared by H/D exchange of 2-methylpropane (isobutane) with a D2O exchanged zeolite. The deuteriated product was obtained with an overall yield of 80.0% (chemical purity: 99.9% and isotopic purity: 98.7%). Perdeuteriated isobutane was prepared by reacting isobutane-2-d1 with 98.0% deuteriated sulfuric acid and was obtained in a total yield of 98.0% (chemical purity: 99.8% and isotopic purity: 97.9%).