191744-13-5 Usage
Description
CX614 is a compound belonging to a series of AMPA modulators, specifically designed to target and modulate the activity of metabotropic AMPA receptors. It is a white to off-white solid, which indicates its solid-state chemical properties.
Uses
Used in Pharmaceutical Industry:
CX614 is used as a modulator for metabotropic AMPA receptors, which play a crucial role in various neurological processes and conditions. Its application in this industry is primarily for the development of potential therapeutic agents that can modulate the activity of these receptors, thereby providing treatment options for a range of neurological disorders.
Used in Research Applications:
In the field of scientific research, CX614 is used as a research tool to study the function and role of metabotropic AMPA receptors in cellular processes and neurological conditions. Its ability to modulate these receptors makes it a valuable compound for understanding the underlying mechanisms and pathways involved in various diseases and disorders.
Used in Drug Development:
CX614 is used as a lead compound in the development of new drugs targeting metabotropic AMPA receptors. Its chemical properties and receptor specificity make it a promising candidate for further optimization and modification to improve its efficacy, selectivity, and safety profile for potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 191744-13-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,7,4 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 191744-13:
(8*1)+(7*9)+(6*1)+(5*7)+(4*4)+(3*4)+(2*1)+(1*3)=145
145 % 10 = 5
So 191744-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO4/c15-13-8-6-10-11(17-5-4-16-10)7-9(8)18-12-2-1-3-14(12)13/h6-7,12H,1-5H2
191744-13-5Relevant articles and documents
Predictably selective (sp3)C-O bond formation through copper catalyzed dehydrogenative coupling: Facile synthesis of dihydro-oxazinone derivatives
Modak, Atanu,Dutta, Uttam,Kancherla, Rajesh,Maity, Soham,Bhadra, Mohitosh,Mobin, Shaikh M.,Maiti, Debabrata
supporting information, p. 2602 - 2605 (2014/06/09)
An intramolecular dehydrogenative (sp3)C-O bond formation in salicylamides can be initiated by an active Cu/O2 species to generate pharamaceutically relevant dihydro-oxazinones. Experimental findings suggest that stereoelectronic parameters in both coupling partners are controlling factors for site selectivity in bond formation. Mechanistic investigations including isotope labeling, kinetic studies helped to propose a catalytic cycle. The method provides a convenient synthesis of an investigational new medicine CX-614, which has potential in finding treatment for Parkinson's and Alzheimer's diseases.