19209-60-0

Basic information

• Product Name: 1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone
• Synonyms: 1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone;5-Acetyl-5H-dibenz[b,f]azepine;N-Acetyl IMinostilbene
• CAS NO: 19209-60-0
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• Mol File: 19209-60-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone(19209-60-0)
• EPA Substance Registry System: 1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone(19209-60-0)

Safety Data

• Hazardous Substances Data: 19209-60-0(Hazardous Substances Data)

Usage

Description

1-(5H-Dibenzo[b,f]azepine-5-yl)ethanone, commonly known as carbamazepine, is a chemical compound with the molecular formula C16H13NO. It is a yellow crystalline solid that serves as a medication for various neurological conditions.

Uses

Used in Pharmaceutical Industry:
Carbamazepine is used as an anticonvulsant for the treatment of epilepsy, as it helps in stabilizing electrical activity in the brain and reducing the occurrence of seizures. It is also utilized as a mood stabilizer in the treatment of bipolar disorder, managing the extreme shifts in mood and behavior associated with the condition.
Additionally, carbamazepine is used as an analgesic for the treatment of trigeminal neuralgia, a chronic pain condition that affects the face. It aids in alleviating the severe, sudden, and recurrent facial pain characteristic of this disorder.

Upstream product

• 4614-45-3 5-acetyl-10,11-dibromo-10,11-dihydro-5H-dibenzo[b,f]azepine 
• 7381-15-9 1,2-diphenyl-1,2-disodiumethane 

Downstream Products

• 3787-10-8 1,4-Dihydro-1,2,4,5-tetrazin-3,6-dicarbonsaeuredimethylester 
• 256-96-2 dibenzoazepine 
• 1799295-84-3 C₂₆H₁₈N₂ 
• 21737-58-6 10,11-dihydro-5H-dibenzo[b,f]azepin-10-one 
• 84142-15-4 dimethyl-N,N ethyl-5 5H-dibenzazepine-10-ethanamine 
• 28291-63-6 5-acetyl-10-oxo-10,11-dihydro-5H-dibenzazepine 
• 4698-11-7 10-methoxy-5H-dibenzo[b,f]azepine 
• 153261-62-2 5-acetyl-10-methoxy-5H-dibenzazepine 
• 117600-98-3 (3aS,12bS)-8-Acetyl-1-phenyl-1,3a,8,12b-tetrahydro-1,2,8-triaza-dibenzo[e,h]azulene-3-carboxylic acid ethyl ester 
• 117600-95-0 1-((3aS,12bS)-1,3-Diphenyl-3a,12b-dihydro-1H-1,2,8-triaza-dibenzo[e,h]azulen-8-yl)-ethanone 
• 117600-96-1 1-((3aR,12bR)-3-Phenyl-1-p-tolyl-3a,12b-dihydro-1H-1,2,8-triaza-dibenzo[e,h]azulen-8-yl)-ethanone 
• 117600-97-2 1-[(3aS,12bS)-3-(4-Chloro-phenyl)-1-phenyl-3a,12b-dihydro-1H-1,2,8-triaza-dibenzo[e,h]azulen-8-yl]-ethanone 

Relevant articles and documents

A new and highly effective organometallic approach to 1,2-dehalogenations and related reactions

We investigated the reductive elimination of several functionalized and non-functionalized vic-dibromides with 1,2-diphenyl-, 1,1,2,2-tetraphenyl- and 1-phenyl-2-(2-pyridyl)-1,2-disodioethane. The reaction, involving some of the less expensive organic and inorganic reagents, proceeds under mild conditions, and is tolerant of a variety of functional groups. Extension of this procedure to similar 1,2-disubstituted compounds was also investigated. Reductive eliminations run on stereochemical probe compounds strongly suggest that this reaction proceeds via a "single electron" reductive elimination reaction pathway.