19217-50-6

Basic information

• Product Name: 3-methoxy-4-methylphenol
• Synonyms: 3-methoxy-4-methylphenol
• CAS NO: 19217-50-6
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.1638
• Mol File: 19217-50-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 240.3 °C at 760 mmHg
• Flash Point: 116.4 °C
• Appearance: /
• Density: 1.078 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-methoxy-4-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxy-4-methylphenol(19217-50-6)
• EPA Substance Registry System: 3-methoxy-4-methylphenol(19217-50-6)

Safety Data

• Hazardous Substances Data: 19217-50-6(Hazardous Substances Data)

Usage

General Description

3-Methoxy-4-methylphenol, also known as guaiacol, is a chemical compound with a molecular formula C7H8O2. It is a colorless to pale yellow liquid with a distinct aromatic odor. 3-Methoxy-4-methylphenol is commonly found in wood smoke, and it is also used as a flavoring agent in food and beverages. It has antiseptic and expectorant properties and is used in pharmaceuticals, particularly in the production of cough syrups and throat lozenges. It is also used as a precursor in the production of various fragrances and as a reagent in organic synthesis. Additionally, guaiacol has been studied for its potential anti-inflammatory and antioxidant effects.

Upstream product

• 18278-34-7 4-hydroxy-2-methoxybenzaldehyde 
• 13120-77-9 2-methyl-5-nitroanisole 
• 496-73-1 4-methyl resorcinol 
• 77-78-1 dimethyl sulfate 
• 16452-01-0 ortho-cresidine 

Downstream Products

• 589-91-3 p-methylcyclohexanol 
• 1393826-50-0 C₂₂H₂₀N₂O₄ 
• 1311138-53-0 N₁-(6-{[4-methyl-3-(methyloxy)phenyl]oxy}-3-pyridinyl)-D-isovalinamide 
• 1311138-06-3 2-{[4-methyl-3-(methyloxy)phenyl]oxy}-5-nitropyridine 
• 1311137-84-4 1-methyl-2-(methyloxy)-4-[(4-nitrophenyl)oxy]benzene 
• 1311138-09-6 N'-(6-{[4-methyl-3-(methyloxy)phenyl]oxy}-3-pyridinyl)-D-alaninamide 
• 1311138-08-5 1,1-dimethylethyl {(1R)-1-methyl-2-[(6-{[4-methyl-3-(methyloxy)phenyl]oxy}-3-pyridinyl)amino]-2-oxoethyl}carbamate 
• 1311138-07-4 6-{[4-methyl-3-(methyloxy)phenyl]oxy}-3-pyridinamine 
• 1311137-87-7 N'-(4-{[4-methyl-3-(methyloxy)phenyl]oxy}phenyl)-D-alaninamide 

Relevant articles and documents

Ceria-promoted Co@NC catalyst for biofuel upgrade: synergy between ceria and cobalt species

Ceria-promoted Co@NC (NC, N doped carbon) catalysts are prepared by pyrolysis of biomass materials. Characterization results indicate that ceria and Co species facilitate the distribution of each other due to the formation of a Ce-O-Co solid solution. The specific surface area of the catalyst increased from 378.77 to 537.7 m2g?1viathe introduction of ceria. The electron transfer from Co to Ce further enhanced their interaction, and Co species facilitate the formation of more defective oxygen vacancies on ceria, which are beneficial to the activities of catalytic hydrogenation and catalytic transfer hydrogenation (CTH), respectively. Thus, Co/Ce@NC (0.99% Co loading) pyrolyzed at 850 °C exhibits excellent performance in the hydrodeoxygenation (HDO) of vanillin with high metal utilization. Catalytic hydrogenation and CTH coexisted in the presence of H2and ethanol, and >99% yield of creosol can be obtained in each of them. The reaction processes are monitored. No intermediate is found in aqueous media, while ethoxymethyl-4-methoxy-2-phenol is detected in ethanol. Moreover, Co/Ce@NC presents outstanding stability and general applicability. This work provides new insights into the construction of M@NC (M, metal) catalysts and the HDO process of biofuel upgrade.

SUBSTITUTED-PYRIDINYL COMPOUNDS AND USES THEREOF

The present application relates generally to compounds useful for the treatment and/or enhancement of cognitive dysfunction and negative symptoms associated with CNS disorders where the circuitry involving fast spiking PV+ interneurons and the production of cortical gamma oscillations is disrupted. The subject disclosure enables the manufacture of medicaments as well as compositions containing same for use in methods of therapy and prophylaxis of cognitive dysfunction and negative symptoms.

HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS

The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.