192211-57-7

Basic information

• Product Name: ((2S,3R,4R,5R)-2-Benzylamino-3,4,6-tris-benzyloxy-1,1-difluoro-5-hydroxy-hexyl)-phosphonic acid diethyl ester
• CAS NO: 192211-57-7
• Molecular Weight: 697.756
• Mol File: 192211-57-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((2S,3R,4R,5R)-2-Benzylamino-3,4,6-tris-benzyloxy-1,1-difluoro-5-hydroxy-hexyl)-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: ((2S,3R,4R,5R)-2-Benzylamino-3,4,6-tris-benzyloxy-1,1-difluoro-5-hydroxy-hexyl)-phosphonic acid diethyl ester(192211-57-7)
• EPA Substance Registry System: ((2S,3R,4R,5R)-2-Benzylamino-3,4,6-tris-benzyloxy-1,1-difluoro-5-hydroxy-hexyl)-phosphonic acid diethyl ester(192211-57-7)

Safety Data

• Hazardous Substances Data: 192211-57-7(Hazardous Substances Data)

Upstream product

• 1478-53-1 Diethyl difluoromethylphosphonate 
• 151593-17-8 N-benzyl-2,3,5-tri-O-benzyl-D-arabinofuranosylamine 
• 100-46-9 benzylamine 
• 160549-10-0 2,3,5-tri-O-benzyl-D-arabinofuranose 

Downstream Products

• 192211-62-4 [((2S,3R,4R,5R)-1-Benzyl-3,4-bis-benzyloxy-5-benzyloxymethyl-pyrrolidin-2-yl)-difluoro-methyl]-phosphonic acid diethyl ester 

Relevant articles and documents

Synthesis of (difluoromethyl)phosphonate azasugars designed as inhibitors for glycosyl transferases

Polyhydroxylated pyrrolidines (azasugars) bearing a (difluoromethylene)phosphonate group at the pseudoanomeric position are prepared by nucleophilic opening of arabino-, ribo- and xylo-furanosylamine with diethyl (lithiodifluoromethyl)phosphonate followed by cyclisation of the amino phosphonate products obtained.