19226-37-0

Basic information

• Product Name: 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one
• Synonyms: 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one
• CAS NO: 19226-37-0
• Molecular Weight: 193.159
• Mol File: 19226-37-0.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one(19226-37-0)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one(19226-37-0)

Safety Data

• Hazardous Substances Data: 19226-37-0(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 10507-69-4 4-methoxybenzohydroxamic acid 
• 121-98-2 methyl 4-methoxybenzoate 
• 530-62-1 1,1'-carbonyldiimidazole 
• 10364-93-9 1-(4-methoxybenzoyl)-imidazole 
• 100-09-4 4-methoxybenzoic acid 

Downstream Products

• 1377585-48-2 4-methoxy-N-(methyl(oxo)(phenyl)-λ⁶-sulfanylidene)benzamide 
• 1642140-26-8 N-(4-methoxylbenzoyl) methyl phenyl sulfimide 
• 1627204-18-5 N-(4-methoxybenzoyl) cyclohexylmethylsulfimide 
• 58754-35-1 4-methoxy-N-(2'-formylphenyl)benzamide 
• 59849-55-7 3-(4-methoxyphenyl)-1-methyl-1-phenylurea 
• 1402931-98-9 [N-(p-methoxyphenyl)-β-(p-fluorophenyl)-β-oxo]propanamide 
• 1037-75-8 4-Chlor-benzoylessigsaeure-<4-methoxy-anilid> 
• 968-30-9 N-(4-methoxyphenyl)-3-oxo-3-(p-tolyl)propanamide 
• 41085-20-5 N-3-bis(4-methoxyphenyl)-3-oxopropanamide 
• 965-50-4 N-(4-methoxyphenyl)-3-oxo-3-phenylpropanamide 
• 94538-56-4 4-methoxy-2-(4-methoxyphenyl)quinazoline 
• 81316-49-6 2-(4-methoxyphenyl)-5-phenyl-4,5-dihydrooxazole 
• 26977-47-9 N³-(4-methoxyphenyl)-1H-indole-3-carboxamide 

Relevant articles and documents

Cu(II)-Catalyzed C-H Amidation/Cyclization of Azomethine Imines with Dioxazolones via Acyl Nitrenes: A Direct Access to Diverse 1,2,4-Triazole Derivatives

We report a Cu(II)-catalyzed C-H amidation/cyclization of azomethine imines with dioxazolones as acyl nitrene transfer reagents under additive-and ligand-free conditions. An array of 1,2,4-triazolo[1,5-a]pyridine derivatives were afforded in moderate to good yields with excellent functional group tolerance. In addition, scale-up reaction and photoluminescence properties were discussed.

Silver-Catalyzed Acyl Nitrene Transfer Reactions Involving Dioxazolones: Direct Assembly of N-Acylureas

Dioxazolones and isocyanides are useful synthetic building blocks, and have attracted significant attention from researchers. However, the silver-catalyzed nitrene transfer reaction of dioxazolones has not been investigated to date. Herein, a silver-catalyzed acyl nitrene transfer reaction involving dioxazolones, isocyanides, and water was realized in the presence of Ag2O to afford a series of N-acylureas in moderate to good yields.

Thioether-Directed NiH-Catalyzed Remote γ-C(sp3)-H Hydroamidation of Alkenes by 1,4,2-Dioxazol-5-ones

A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote methylene C-H bond amidation of unactivated alkenes. Due to the preference for five-membered nickelacycle formation, the chain-walking isomerization initiated by the NiH insertion to an alkene can be terminated at the γ-methylene site remote from the alkene moiety. By employing 2,9-dibutyl-1,10-phenanthroline as the ligand and dioxazolones as the reagent, the amidation occurs at the γ-C(sp3)-H bonds to afford the amide products in up to 90% yield (>40 examples) with remarkable regioselectivity (up to 24:1 rr).