192440-12-3

Basic information

• Product Name: 2-Propen-1-one, 1-(2-hydroxyphenyl)-2-phenyl-
• CAS NO: 192440-12-3
• Molecular Formula: C15H12O2
• Molecular Weight: 224.259
• Mol File: 192440-12-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(2-hydroxyphenyl)-2-phenyl-(192440-12-3)
• EPA Substance Registry System: 2-Propen-1-one, 1-(2-hydroxyphenyl)-2-phenyl-(192440-12-3)

Safety Data

• Hazardous Substances Data: 192440-12-3(Hazardous Substances Data)

Upstream product

• 1071137-16-0 2-(1-Ethoxy-ethoxy)-2-(2-methoxymethoxy-phenyl)-4-nitro-3-phenyl-butyronitrile 
• 102-96-5 (2-nitroethenyl)benzene 
• 42772-82-7 1-(2-Hydroxyphenyl)-2-phenylpropan-1-one 
• 90-02-8 salicylaldehyde 
• 536-74-3 phenylacetylene 
• 412339-67-4 1-(2-Methoxymethoxy-phenyl)-2-phenyl-propenone 

Downstream Products

• 574-12-9 isoflavone 
• 97904-75-1 isoflavanone 

Relevant articles and documents

Direct syntheses of benzofuran-2(3H)-ones and benzofuran-3(2H)-ones from 1-(2-hydroxyphenyl)alkan-1-ones by CuBr2 or CuCl2

New syntheses of benzofuran-2(3H)-ones and benzofuran-3(2H)-ones from 1-(2-hydroxyphenyl)alkan-1-ones via oxidative cyclization by CuBr2 or CuCl2 are described. A new synthesis of 1H-isochromene-1,4(3H)- diones via similar procedures is also described. Copyright

Reaction of 2-hydroxybenzaldehydes with alkynes, alkenes, or allenes via cleavage of the aldehyde C-H bond using a rhodium catalyst system

2-Hydroxybenzaldehydes smoothly and efficiently react with various internal and terminal alkynes accompanied by cleavage of the aldehyde C-H bond by using a rhodium-based catalyst system of [RhCl(cod)]2/dppf/Na2CO3 [cod = 1,5-cyclooctadiene; dppf = 1,1'-bis(diphenylphosphino)ferrocene] to give the corresponding 2-alkenoylphenols in good to excellent yields. The regioselectivity of the reaction depends on the substituents of acetylene; an oxygen function on the propargylic position shows a considerable directing effect. The aldehydes can also react with some alkenes or allenes, such as triethylvinylsilane and 2-norbornene or 3-methyl-1,2-butadiene and 1,2- nonadienes, in place of alkynes.