192460-93-8

Basic information

• Product Name: 8-Oxabicyclo[3.2.1]oct-2-ene-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester
• CAS NO: 192460-93-8
• Molecular Formula: C15H15BrO3
• Molecular Weight: 323.186
• Mol File: 192460-93-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 8-Oxabicyclo[3.2.1]oct-2-ene-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Oxabicyclo[3.2.1]oct-2-ene-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester(192460-93-8)
• EPA Substance Registry System: 8-Oxabicyclo[3.2.1]oct-2-ene-2-carboxylic acid, 3-(4-bromophenyl)-, methyl ester(192460-93-8)

Safety Data

• Hazardous Substances Data: 192460-93-8(Hazardous Substances Data)

Upstream product

• 52409-22-0 tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ 
• 462-95-3 formaldehyde diethyl acetal 
• 5467-74-3 4-Bromophenylboronic acid 
• 497-19-8 sodium carbonate 
• 192460-63-2 2-carbomethoxy-3-{[(trifluoromethyl)sulfonyl]oxy}-8-oxabicyclo[3.2.1]-2-octene 
• 73774-63-7 2-carbomethoxy-8-oxabicyclo[3.2.1]octanone 

Downstream Products

• 192461-00-0 2-carbomethoxy-3-(4-iodophenyl)-8-oxabicyclo[3.2.1]-2-octene 

Relevant articles and documents

Tropane analogs and methods for inhibition of monoamine transport

New tropane analogs that bind to monoamine transporters are described, particularly, 8-aza, 8carbo and 8-oxo tropanes having 6- or 7-substituents. The compounds of the present invention can be racemic, pure R-enantiomers, or pure S-enantiomers. Certain preferred compounds of the present invention have a high selectivity for the DAT versus the SERT. Also described are pharmaceutical therapeutic compositions comprising the compounds formulated in a pharmaceutically acceptable carrier and a method for inhibiting 5-hydroxy-tryptamine reuptake of a monoamine transporter by contacting the monoamine transporter with a 5-hydroxytryptamine reuptake inhibiting amount of a compound of the present invention. Preferred monoamine transporters for the practice of the present invention include the dopamine transporter, the serotonin transporter and the norepinephrine transporter.

Tropane analogs and methods for inhibition of monoamine transport

New tropane analogs that bind to monoamine transporters are described, particularly, 8-aza, 8carbo and 8-oxo tropanes having 6- or 7-substituents. The compounds of the present invention can be racemic, pure R-enantiomers, or pure S-enantiomers. Certain pr