1925-71-9

Basic information

• Product Name: 1,3,4-Thiadiazole, 2-(methylthio)-5-phenyl-
• CAS NO: 1925-71-9
• Molecular Formula: C9H8N2S2
• Molecular Weight: 208.308
• Mol File: 1925-71-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,3,4-Thiadiazole, 2-(methylthio)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Thiadiazole, 2-(methylthio)-5-phenyl-(1925-71-9)
• EPA Substance Registry System: 1,3,4-Thiadiazole, 2-(methylthio)-5-phenyl-(1925-71-9)

Safety Data

• Hazardous Substances Data: 1925-71-9(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound

Structure

Five-membered ring with three carbon atoms, one nitrogen atom, and one sulfur atom

Substituents

2-(methylthio) and 5-phenyl groups

Pharmacological properties

Antimicrobial, antifungal, and anticancer activities

Applications

Medicinal and agricultural uses, development of new drugs and pharmaceutical products

Importance

Presence of methylthio and phenyl groups enhances biological activities, making it a significant molecule in medicinal chemistry and drug discovery research

Upstream product

• 5585-19-3 2-phenyl-1,3,4-thiadiazole-5(4H)-thione 
• 74-88-4 methyl iodide 
• 7449-45-8 methyl N'-benzoylhydrazinocarbodithioate 
• 186581-53-3 diazomethane 
• 19703-86-7 Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion 
• 7484-46-0 S-methyl benzenylmethylene hydrazine dithiocarboxylate 
• 65-85-0 benzoic acid 
• 93-58-3 benzoic acid methyl ester 
• 74-87-3 methylene chloride 
• 5585-19-3 5-phenyl-1,3,4-thiadiazole-2-thiol 
• 613-94-5 benzoic acid hydrazide 
• 21048-05-5 N-methylbenzothiohydrazide 
• 20605-40-7 thiobenzoylhydrazine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 131239-81-1 4-nitro-benzaldehyde (3-methyl-5-phenyl-3H-[1,3,4]thiadiazol-2-ylidene)-hydrazone 
• 92474-95-8 3-methyl-5-phenyl-3H-[1,3,4]thiadiazol-2-one hydrazone 
• 5771-12-0 3-methyl-2-methylsulfanyl-5-phenyl-[1,3,4]thiadiazolium; methyl sulfate 
• 131620-14-9 3-methyl-5-phenyl-3H-[1,3,4]thiadiazol-2-one benzoylhydrazone 
• 86738-35-4 2-(methylsulfonyl)-5-phenyl-1,3,4-thiadiazole 

Relevant articles and documents

Thiadiazole sulfone compound as well as preparation method and application thereof

The invention relates to the field of agricultural fungicides and discloses a thiadiazole sulfone compound as well as a preparation method and application thereof. The compound has a structure expressed by a formula (I) which is as shown in the descriptio

Synthesis and anticonvulsant activity of 5-aryl-1,3,4-thiadiazole derivatives

5-Aryl-1,3,4-thiadiazole derivatives were synthesized and tested for anticonvulsant activity using the pentylenetetrazole-induced lethal convulsion test. The results showed that 2-amino derivatives have anticonvulsant activity (LD50 > 500 mg kg-1) and this effect was not mediated through benzodiazepine receptors. The fluoro electron-withdrawing substituent on the phenyl ring did not potentiate the activity of the compounds.

A novel synthesis of thiadiazole and thiadiazine derivatives via charge-transfer complexation

S-Methyl dithiocarbazate 2 reacted with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) via the formation of charge-transfer (CT) complexes to give the thiadiazine derivative 19.The azomethine derivatives 1a-f reacted with both DDQ and 2,3-dicyano-1,4-naphthoquinone (DCNQ) via CT complexation to afford the bisazines 10a-f, the thiadiazole derivatives 11a-f and DDQ-H2 (12) as well as DCNQ-H2 (13).The mechanism of the formation of products 10-13 and 19 is discussed. - Keywords: charge-transfer complex; 1,3,4-thiadiazoles; 1,3,4-thiadiazines; dithiocarbazates; quinone.