192649-51-7 Usage
Description
(R,R)-1,2-Ph2-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine is a chiral ligand used in organic synthesis and catalysis. It is characterized by its two phenyl groups and two N,N'-bis(mesitylmethylidene)ethane-1,2-diamine groups connected by an ethane-1,2-diamine backbone. (R,R)-1,2-Ph2-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine's chiral nature enables selective binding to transition metals, which is essential for enantioselective transformations.
Uses
Used in Asymmetric Catalysis:
(R,R)-1,2-Ph2-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine is used as a chiral ligand in transition metal-catalyzed asymmetric reactions for enhancing enantioselectivity and reaction efficiency.
Used in Organic Synthesis:
In the field of organic synthesis, (R,R)-1,2-Ph2-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine is employed as a chiral ligand to facilitate various synthetic transformations, including asymmetric hydrogenation and hydroformylation.
Used in Pharmaceutical Industry:
(R,R)-1,2-Ph2-N,N'-bis(mesitylmethylidene)ethane-1,2-diamine is used as a key intermediate in the synthesis of chiral pharmaceuticals, contributing to the development of more effective and selective drugs.
Used in Chemical Research:
This chiral ligand is also utilized in academic and industrial research for exploring new catalytic processes and advancing the understanding of asymmetric catalysis mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 192649-51-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,6,4 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 192649-51:
(8*1)+(7*9)+(6*2)+(5*6)+(4*4)+(3*9)+(2*5)+(1*1)=167
167 % 10 = 7
So 192649-51-7 is a valid CAS Registry Number.
192649-51-7Relevant articles and documents
Stereospecific diaza-cope rearrangement driven by steric strain
Kim, Hyunwoo,Nguyen, Yen,Lough, Alan J.,Chin, Jik
, p. 8678 - 8681 (2008)
(Chemical Equation Presented) Bucklingunder the strain: Steric strain was used to drive the diaza-Cope rearrangement to completion (see scheme) with a high degree of stereospecificity (>99.5% ee), as evidenced by chiral-phase HPLC and crystal data. There is good agreement between the experimental and computational values for the rate and equilibrium constants for the rearrangement.
