1927-43-1

Basic information

• Product Name: 2-chloro-10H-phenothiazine 5-oxide
• Synonyms: 10H-Phenothiazine, 2-chloro-, S-oxide
• CAS NO: 1927-43-1
• Molecular Formula: C₁₂H₈ClNOS
• Molecular Weight: 249.716
• Mol File: 1927-43-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 447.1°C at 760 mmHg
• Flash Point: 224.2°C
• Density: 1.55g/cm³
• Vapor Pressure: 3.46E-08mmHg at 25°C
• Refractive Index: 1.773
• CAS DataBase Reference: 2-chloro-10H-phenothiazine 5-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-10H-phenothiazine 5-oxide(1927-43-1)
• EPA Substance Registry System: 2-chloro-10H-phenothiazine 5-oxide(1927-43-1)

Safety Data

• Hazardous Substances Data: 1927-43-1(Hazardous Substances Data)

Upstream product

• 92-39-7 2-chlorophenothiazine 
• 50-53-3 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine 

Relevant articles and documents

Photodecomposition of some substituted phenothiazines

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Sulfoxide and sulfone compounds, as well as selective synthesis method and application thereof

The invention discloses a method for selectively synthesizing a sulfoxide compound shown as a formula (II) and a sulfone compound shown as a formula (III). In a reaction solvent, thioether (I) is usedas a reaction raw material and oxygen as an oxidation reagent, under the catalytic action of visible light and a photosensitive reagent; under the assistance of an additive, when a large-polarity proton-containing additive such as an acid and an alcohol or a solvent or an additive with excellent electron donating ability is used, a sulfoxide compound (II) is selectively generated; and when a small-polarity aprotic additive or a solvent is used, a sulfone compound (III) is selectively generated. The synthesis method has the advantages of easily available and cheap raw materials, simple reaction operation, mild reaction conditions, high yield and excellent functional group tolerance. According to the invention, synthesis and modification of some medicines are realized, and an efficient method for selectively constructing sulfoxide and sulfone compounds is provided for medicinal chemistry research.