192725-70-5

Basic information

• Product Name: 2S-(1-Pyrrolidin-2,5-dionyl)-3-methyl-butanoic acid benzyl ester
• Synonyms: 2S-(1-Pyrrolidin-2,5-dionyl)-3-methyl-butanoic acid benzyl ester
• CAS NO: 192725-70-5
• Molecular Weight: 289.331
• Mol File: 192725-70-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2S-(1-Pyrrolidin-2,5-dionyl)-3-methyl-butanoic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2S-(1-Pyrrolidin-2,5-dionyl)-3-methyl-butanoic acid benzyl ester(192725-70-5)
• EPA Substance Registry System: 2S-(1-Pyrrolidin-2,5-dionyl)-3-methyl-butanoic acid benzyl ester(192725-70-5)

Safety Data

• Hazardous Substances Data: 192725-70-5(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 21760-98-5 L-valine benzyl ester 
• 2592-95-2 benzotriazol-1-ol 
• 713543-38-5 (S)-2-(3-Carboxy-propionylamino)-3-methyl-butyric acid benzyl ester 

Relevant articles and documents

Novel lopinavir analogues incorporating heterocyclic replacements of six-member cyclic urea - Synthesis and structure-activity relationships

The HIV protease inhibitor ABT-378 (lopinavir) has a six-member cyclic urea in the P-2 position. A series of analogues in which the six-member cyclic urea is replaced by various heterocycles was synthesized and the structure-activity relationships explored.

RETROVIRAL PROTEASE INHIBITING COMPOUNDS

A compound of the formula: STR1 is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.