19275-82-2

Basic information

• Product Name: 1H-Benzimidazole,2-(1-chloroethyl)-(9CI)
• Synonyms: 1H-Benzimidazole,2-(1-chloroethyl)-(9CI);2-(1-chloroethyl)-1H-benzimidazole hydrochloride;2-(1-chloroethyl)-1H-benzo[d]imidazole hydrochloride
• CAS NO: 19275-82-2
• Molecular Formula: C₉H₉ClN₂
• Molecular Weight: 180.63416
• Product Categories: BENZIMIDAZOLE
• Mol File: 19275-82-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole,2-(1-chloroethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2-(1-chloroethyl)-(9CI)(19275-82-2)
• EPA Substance Registry System: 1H-Benzimidazole,2-(1-chloroethyl)-(9CI)(19275-82-2)

Safety Data

• Hazardous Substances Data: 19275-82-2(Hazardous Substances Data)

Usage

General Description

1H-Benzimidazole,2-(1-chloroethyl)-(9CI) is a chemical compound that is classified as an organic compound. It is a benzimidazole derivative with a substituted chloroethyl group. 1H-Benzimidazole,2-(1-chloroethyl)-(9CI) may have various applications in organic synthesis and pharmaceutical research due to its unique chemical structure. It may be used as a building block in the synthesis of complex organic molecules or as a precursor in the production of certain pharmaceutical drugs. Additionally, it may also have potential applications in the fields of materials science and chemical engineering. However, it is important to handle and use this compound with caution, as it may have potential hazards and risks associated with its use.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 598-78-7 (R,S)-2-chloropropionic acid 
• 7647-01-0 hydrogenchloride 
• 16414-04-3 1-benzimidazol-2-ylethanol 

Downstream Products

• 952424-77-0 2-(1-benzenesulfonyl-ethyl)-1H-benzimdazole 
• 952424-87-2 2-(1-chloroethyl)-1-benzyl-benzimidazole 
• 952424-76-9 2-[1-(toluene-4-sulfonyl)-ethyl]-1H-benzimidazole 
• 58282-03-4 1-methyl-2-(α-chloroethyl)benzimidazole 
• 180137-65-9 4-(4-chloro-phenyl)-1-methyl-1H-2-thia-4,4a,9-triaza-fluorene-3-thione 
• 180137-57-9 (4-chloro-phenyl)-dithiocarbamic acid 1-(1H-benzoimidazol-2-yl)-ethyl ester 
• 103153-63-5 4-[1-(1H-benzimidazol-2-yl)-ethylamino]-benzoic acid ethyl ester 
• 95943-57-0 N-{4-[(Ξ)-1-(1H-benzimidazol-2-yl)-ethylamino]-benzoyl}-L-glutamic acid diethyl ester 
• 3176-70-3 2-(1-mercaptoethyl)benzimidazole 
• 153430-86-5 1-Methyl-4-phenyl-1H-2-thia-4,4a,9-triaza-fluorene-3-thione 

Relevant articles and documents

Synthesis and in vitro antifungal evaluation of benzoimidazolyl-piperazinyl-phenylmethanone derivatives

Benzimidazole and piperazines are the important pharmacophores in the structures of many antifungal compounds. Further, the phenylmethanone are also a unique class of compounds whose antifungal profile is not much exploited. So to exploit their antifungal potential we have selected these three combinations and framed the novel parent structure for our research work. In this study a novel series of benzimidazoles derivatives was synthesized by microwave irradiation and characterized by 1H NMR, 13C NMR, Infra Red (IR), and Mass Spectroscopy (MS), and by elemental analysis. The screening of compound for in vitro (turbidimetric method) antifungal activity against C.albicans revealed activity in many of the compounds as comparable to that of ketoconazole.

Bicyclic Benzimidazole Compounds and Their Use as Metabotropic Glutamate Receptor Potentiators

Compounds of Formula I: wherein A, B, D, L, R1, R2, R3, R4, m, and n are as defined for Formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.