19277-56-6

Basic information

• Product Name: Benzoic acid, 4-methyl-, butyl ester
• Synonyms: Benzoic acid, 4-methyl-, butyl ester;p-Toluic acid butyl ester
• CAS NO: 19277-56-6
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.25
• Mol File: 19277-56-6.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 268°Cat760mmHg
• Flash Point: 118°C
• Appearance: /
• Density: 0.995g/cm³
• Vapor Pressure: 0.00789mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: Benzoic acid, 4-methyl-, butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-methyl-, butyl ester(19277-56-6)
• EPA Substance Registry System: Benzoic acid, 4-methyl-, butyl ester(19277-56-6)

Safety Data

• Hazardous Substances Data: 19277-56-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O2/c1-3-4-9-14-12(13)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 380481-66-3 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane 
• 71-36-3 butan-1-ol 
• 5456-97-3 N-butyl-4-methylbenzamide 
• 1418228-44-0 diisopropyl 1-(4-(methyl)benzoyl)hydrazine-1,2-dicarboxylate 
• 2947-61-7 (4-methylphenyl)acetonitrile 
• 624-31-7 4-tolyl iodide 
• 13939-06-5 molybdenum hexacarbonyl 
• 109-65-9 1-bromo-butane 
• 104-87-0 4-methyl-benzaldehyde 
• 91763-46-1 1-(butoxymethyl)-4-methylbenzene 
• 65768-10-7 p-methylbenzaldehyde di-n-butyl acetal 
• 874-60-2 4-methyl-benzoyl chloride 
• 619-55-6 para-methylbenzamide 

Downstream Products

• 28129-15-9 2-hydroxyethyl 4-methylbenzoate 
• 86582-55-0 C₁₂H₁₅BrO₂ 
• 51638-13-2 dimethyl [2-(4-methylphenyl)-2-oxoethyl]phosphonate 

Relevant articles and documents

Mild and efficient method for the cleavage of cyclic and acyclic ethers by iodine under solvent-free conditions

Ethers undergo smooth cleavage with acyl chlorides in the presence of a catalytic amount of elemental iodine under extremely mild conditions to give the corresponding halo esters. This new procedure offers significant advantages such as high conversions, short reaction times and enhanced selectivity together with mild reaction conditions, which makes it an attractive strategy.

Zr-MOF-808 as Catalyst for Amide Esterification

In this work, zirconium-based metal–organic framework Zr-MOF-808-P has been found to be an efficient and versatile catalyst for amide esterification. Comparing with previously reported homogeneous and heterogeneous catalysts, Zr-MOF-808-P can promote the reaction for a wide range of primary, secondary and tertiary amides with n-butanol as nucleophilic agent. Different alcohols have been employed in amide esterification with quantitative yields. Moreover, the catalyst acts as a heterogeneous catalyst and could be reused for at least five consecutive cycles. The amide esterification mechanism has been studied on the Zr-MOF-808 at molecular level by in situ FTIR spectroscopic technique and kinetic study.

A Straightforward Conversion of Activated Amides and Haloalkanes into Esters under Transition-Metal-Free Cs 2 CO 3 /DMAP Conditions

The esterification of activated amides, N -acylsaccharins, under transition-metal-free conditions with good functional group tolerance has been developed, resulting in C-N cleavage leading to efficient synthesis of a variety of esters in moderate to good yields. This work demonstrates that esterification may proceed by using simple N -acylsaccharins, haloalkanes, and Cs 2 CO 3 as oxygen source.