192803-37-5

Basic information

• Product Name: 3-tert-butyl-2,5-dihydroxy-benzaldehyde
• Synonyms: 3-tert-Butyl-2,5-dihydroxybenzaldehyde; benzaldehyde, 3-(1,1-dimethylethyl)-2,5-dihydroxy-
• CAS NO: 192803-37-5
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 192803-37-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 140-142 °C
• Boiling Point: 295.9°C at 760 mmHg
• Flash Point: 147°C
• Density: 1.179g/cm³
• Vapor Pressure: 0.000843mmHg at 25°C
• Refractive Index: 1.584
• PKA: 10.10±0.23(Predicted)
• CAS DataBase Reference: 3-tert-butyl-2,5-dihydroxy-benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butyl-2,5-dihydroxy-benzaldehyde(192803-37-5)
• EPA Substance Registry System: 3-tert-butyl-2,5-dihydroxy-benzaldehyde(192803-37-5)

Safety Data

• Hazardous Substances Data: 192803-37-5(Hazardous Substances Data)

Usage

General Description

3-tert-butyl-2,5-dihydroxy-benzaldehyde is a chemical compound with the molecular formula C13H16O3. It is also known as 3-(tert-butyl)-2,5-dihydroxybenzaldehyde and is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. 3-tert-butyl-2,5-dihydroxy-benzaldehyde is a white to light yellow solid with a sweet, floral odor. It is soluble in most organic solvents and is commonly used in the production of various fragrances and flavors. Additionally, 3-tert-butyl-2,5-dihydroxy-benzaldehyde has been used in research as a building block for the development of new drugs and other bioactive compounds. However, it is important to handle this chemical with care as it may be harmful if ingested, inhaled, or absorbed through the skin.

Upstream product

• 50-00-0 formaldehyd 
• 155135-23-2 2-(1,1-dimethylethyl)-4-(triisopropylsilyloxy)phenol 
• 246509-53-5 2-hydroxy-5-pivaloyloxy-3-tert-butylbenzaldehyde 
• 66549-79-9 3-(tert-butyl)-4-hydroxyphenyl pivalate 
• 1948-33-0 tert-butylhydroquinone 
• 3421-95-2 4-(benzyloxy)-2-(tert-butyl)phenol 
• 192803-36-4 5-benzyloxy-3-tert-butyl-2-hydroxy-benzaldehyde 
• 155135-24-3 3-tert-butyl-2-hydroxy-5-triisopropylsiloxybenzaldehyde 

Downstream Products

• 360784-98-1 5-[3,5-bis-(4-vinyl-benzyloxy)-benzyloxy]-3-tert-butyl-2-hydroxy-benzaldehyde 
• 360784-99-2 5-{3,5-bis-[3,5-bis-(4-vinyl-benzyloxy)-benzyloxy]-benzyloxy}-3-tert-butyl-2-hydroxy-benzaldehyde 
• 616873-78-0 p-phenylenedioxydiacetic acid di-(3-tert-butyl-5-formyl-4-hydroxy-phenyl)ester 
• 805314-84-5 (4-methoxy-phenoxy)-acetic acid 3-tert-butyl-5-formyl-4-hydroxy-phenyl ester 
• 884539-90-6 {(1R,2R)-2-[(-)-2-(3,5-di-tert-butyl-2-hydroxybenzylideneamino)cyclohexylimino]methyl}-6-tert-butylbenzene-1,4-diol 
• 1033766-43-6 C₁₇H₂₀N₄O₂ 
• 1313716-82-3 3-formyl-5-tert-butyl-4-hydroxyphenyl 3,4,5-tris(dodecyloxy)benzoate 
• 1612884-40-8 C₆₂H₈₂N₄O₁₁ 
• 1612884-44-2 (R,R)-N,N′-bis(3-tert-butyl-5-[3-methoxypropionyloxy]salicylidene)-1,2-cyclohexanediamine 
• 1612884-46-4 C₇₀H₉₄N₄O₁₅ 
• 1612884-37-3 3-[2-(3-tert-butyl-5-formyl-4-hydroxyphenoxycarbonyl)ethoxy]propionic acid 
• 1612884-38-4 C₆₂H₇₈N₂O₁₆ 
• 336195-57-4 (R,R)-N,N′-bis(3-tert-butyl-5-hydroxysalicylidene)-1,2-cyclohexanediamine 
• 1612884-43-1 C₁₅H₂₀O₅ 

Relevant articles and documents

An Amphiphilic (salen)Co Complex – Utilizing Hydrophobic Interactions to Enhance the Efficiency of a Cooperative Catalyst

An amphiphilic (salen)Co(III) complex is presented that accelerates the hydrolytic kinetic resolution (HKR) of epoxides almost 10 times faster than catalysts from commercially available sources. This was achieved by introducing hydrophobic chains that increase the rate of reaction in one of two ways – by enhancing cooperativity under homogeneous conditions, and increasing the interfacial area under biphasic reaction conditions. While numerous strategies have been employed to increase the efficiency of cooperative catalysts, the utilization of hydrophobic interactions is scarce. With the recent upsurge in green chemistry methods that conduct reactions ‘on water’ and at the oil-water interface, the introduction of hydrophobic interactions has potential to become a general strategy for enhancing the catalytic efficiency of cooperative catalytic systems. (Figure presented.).

A broadly applicable and practical oligomeric (salen)Co catalyst for enantioselective epoxide ring-opening reactions

The (salen)Co catalyst (4a) can be prepared as a mixture of cyclic oligomers in a short, chromatography-free synthesis from inexpensive, commercially available precursors. This catalyst displays remarkable enhancements in reactivity and enantioselectivity relative to monomeric and other multimeric (salen)Co catalysts in a wide variety of enantioselective epoxide ring-opening reactions. The application of catalyst 4a is illustrated in the kinetic resolution of terminal epoxides by nucleophilic ring-opening with water, phenols, and primary alcohols; the desymmetrization of meso epoxides by addition of water and carbamates; and the desymmetrization of oxetanes by intramolecular ring opening with alcohols and phenols. The favorable solubility properties of complex 4a under the catalytic conditions facilitated mechanistic studies, allowing elucidation of the basis for the beneficial effect of oligomerization. Finally, a catalyst selection guide is provided to delineate the specific advantages of oligomeric catalyst 4a relative to (salen)Co monomer 1 for each reaction class.

POLYMERIC SALEN COMPOUNDS AND METHODS THEREOF

The present disclosure provides a polymerizable compound of the formula (I) where the R1, R2, R’1, R’2, X1 to X8, Y1, Y2, M and L have any of values as defined in the