1929-89-1

Basic information

• Product Name: N-Phenyl-2-furancarboxamide
• Synonyms: N-Phenyl-2-furancarboxamide;N-Phenylfuran-2-carboxamide;N-phenyl-2-furamide
• CAS NO: 1929-89-1
• Molecular Formula: C₁₁H₉NO₂
• Molecular Weight: 187.19466
• Mol File: 1929-89-1.mol
• Article Data: 48

Chemical Properties

• Boiling Point: 217.9 °C at 760 mmHg
• Flash Point: 85.6 °C
• Appearance: /
• Density: 1.238 g/cm³
• Vapor Pressure: 0.129mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: N-Phenyl-2-furancarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Phenyl-2-furancarboxamide(1929-89-1)
• EPA Substance Registry System: N-Phenyl-2-furancarboxamide(1929-89-1)

Safety Data

• Hazardous Substances Data: 1929-89-1(Hazardous Substances Data)

Usage

Description

N-Phenyl-2-furancarboxamide is a chemical compound with the molecular formula C11H9NO2, known for its insecticidal properties. It is commonly used as a pesticide, disrupting the nervous system of insects, leading to paralysis and death.

Uses

Used in Agriculture:
N-Phenyl-2-furancarboxamide is used as an insecticide for protecting crops from insect infestations, ensuring a healthy and productive yield.
Used in Vector-Borne Disease Control:
N-Phenyl-2-furancarboxamide is studied for its potential use in controlling vector-borne diseases such as malaria and dengue fever, contributing to public health and disease prevention efforts.
It is important to handle N-Phenyl-2-furancarboxamide with care, as it can be toxic to humans and the environment if not used properly.

InChI:InChI=1/C11H9NO2/c13-11(10-7-4-8-14-10)12-9-5-2-1-3-6-9/h1-8H,(H,12,13)

Upstream product

• 62-53-3 aniline 
• 1026046-13-8 2-furanoyl sulfonate 
• 103-71-9 phenyl isocyanate 
• 611-13-2 2-furoic acid methyl ester 
• 609-38-1 furan-2-carboxylic acid amide 
• 2996-92-1 phenyl trimethylsiloxane 
• 186965-61-7 3-(2-furyl)-3-oxo-2-(phenylhydrazono)propanal 
• 614-99-3 Ethyl 2-furoate 
• 527-69-5 2-furancarbonyl chloride 
• 98-95-3 nitrobenzene 
• 144223-33-6 2-furoyl-1H-1,2,3-benzotriazole 
• 95-14-7 1,2,3-Benzotriazole 
• 1373758-56-5 3-(furan-2-yl)-5H-1,4,2-dioxazol-5-one 
• 98-80-6 phenylboronic acid 

Downstream Products

• 10243-03-5 furan-2-carbothioic acid anilide 
• 58472-54-1 5-bromo-furan-2-carboxylic acid-(4-bromo-anilide) 
• 1569-98-8 2-(furan-2-yl)-1,3-benzothiazole 
• 34653-56-0 5-(1,3-benzothiazol-2-yl)furan-2-carbaldehyde 
• 74442-13-0 C₄H₃OC(O)N(SCCl₂CFCl₂)C₆H₅ 
• 74442-14-1 C₄H₃OC(O)N(SCClFCFCl₂)C₆H₅ 
• 6436-22-2 N-phenyl-furan-2-carboximidoyl chloride 
• 1214752-44-9 N-(furan-2-yl(phenylimino)methyl)-N-phenylfuran-2-carboxamide 
• 622804-75-5 5-(2-trifluoromethylphenyl)furan-2-carboxylic acid phenylamide 
• 1404192-00-2 4,5,6-triphenylfuro[2,3-c]pyridin-7(6H)-one 
• 1237829-82-1 2-(furan-2-yl)-4-phenylquinazoline 
• 18249-70-2 1-benzyl-2-(furan-2-yl)-1H-benzo[d]imidazole 
• 6436-38-0 N-benzyl-N'-phenylfuran-2-carboximidamide 
• 98-00-0 (2-furyl)methyl alcohol 

Relevant articles and documents

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Pd(OAc)2/AgOAc catalytic system based bidentate ligand directed regiocontrolled C-H arylation and alkylation of the C-3 position of thiophene- and furan-2-carboxamides

A contemporary method is reported for the Pd(OAc)2/AgOAc catalytic system based bidentate ligand directed, regioselective C-H activation and C-C bond formation at the C-3 position of thiophene- and furan-2-carboxamides, which are derived from 8

A practical and sustainable protocol for direct amidation of unactivated esters under transition-metal-free and solvent-free conditions

In this paper, a NaOtBu-mediated synthesis approach was developed for direct amidation of unactivated esters with amines under transition-metal-free and solvent-free conditions, affording a series of amides in good to excellent yields at room temperature. In particular, an environmentally friendly and practical workup procedure, which circumvents the use of organic solvents and chromatography in most cases, was disclosed. Moreover, the gram-scale production of representative products3a,3wand3auwas efficiently realized by applying operationally simple, sustainable and practical procedures. Furthermore, this approach was also applicable to the synthesis of valuable molecules such as moclobemide (a powerful antidepressant), benodanil and fenfuram (two commercial agricultural fungicides). These results demonstrate that this protocol has the potential to streamline amide synthesis in industry. Meanwhile, quantitative green metrics of all the target products were evaluated, implying that the present protocol is advantageous over the reported ones in terms of environmental friendliness and sustainability. Finally, additional experiments and computational calculations were carried out to elucidate the mechanistic insight of this transformation, and one plausible mechanism was provided on the basis of these results and the related literature reports.

Visible-Light-Promoted Iron-Catalyzed N-Arylation of Dioxazolones with Arylboronic Acids

A visible-light-promoted and simple iron salt-catalyzed N-arylation was achieved efficiently under external photosensitizer-free conditions. Arylboronic acids and bench-stable dioxazolones were used for this cross-coupling reaction. This reaction features high reactivity, wide substrate scope, good functional group tolerance, simple operation procedure, and mild reaction conditions. Preliminary mechanistic investigations were conducted to support a radical pathway. This method may contribute to shift the paradigm of iron-catalyzed C-N bond construction and nitrene transfer chemistry.