1930-54-7

Basic information

• Product Name: 4-bromo-9-methoxy-7H-furo[3,2-g]chromen-7-one
• CAS NO: 1930-54-7
• Molecular Formula: C₁₂H₇BrO₄
• Molecular Weight: 295.0856
• Mol File: 1930-54-7.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 464.1°C at 760 mmHg
• Flash Point: 234.5°C
• Density: 1.694g/cm³
• Vapor Pressure: 8.63E-09mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 4-bromo-9-methoxy-7H-furo[3,2-g]chromen-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-9-methoxy-7H-furo[3,2-g]chromen-7-one(1930-54-7)
• EPA Substance Registry System: 4-bromo-9-methoxy-7H-furo[3,2-g]chromen-7-one(1930-54-7)

Safety Data

• Hazardous Substances Data: 1930-54-7(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 298-81-7 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 
• 7726-95-6 bromine 
• 485-90-5 hydrangetin 
• 29267-67-2 2-methoxyresorcinol 
• 87-66-1 2-hydroxyresorcinol 
• 482-44-0 imperatorin 
• 1930-56-9 4-nitro-9-methoxy-7H-furo<3,2-g><1>benzopyran-7-one 
• 83660-02-0 2,3,4-tribromo-9-methoxy-2,3-dihydro-furo[3,2-g]chromen-7-one 
• 56-23-5 tetrachloromethane 
• 128-08-5 N-Bromosuccinimide 
• 49739-65-3 4-amino-9-methoxy-7H-furo<3,2-g><1>benzopyran-7-one 

Downstream Products

• 1426427-38-4 4-(9-methoxy-7-oxo-7H-furo[3,2-g]chromen-4-yl)benzaldehyde 
• 1426427-39-5 4-(9-methoxy-7-oxo-7H-furo[3,2-g]chromen-4-yl)benzoic acid 
• 1930-56-9 4-nitro-9-methoxy-7H-furo<3,2-g><1>benzopyran-7-one 

Relevant articles and documents

Synthesis and fluorescent study of 5-phenyl furocoumarin derivatives as vasodilatory agents

Two series of 5-phenyl furocoumarin derivatives were designed and prepared based on our previous research. All new compounds were characterized by 1H NMR, 13C NMR and mass spectra. Furthermore, they were screened for their vasodilato

Synthesis and evaluation of linear furanocoumarins as potential anti-breast and anti-prostate cancer agents

A series of 22 furanocoumarin derivatives were synthesized and evaluated for cytotoxicity against breast cancer (MCF-7 and MDA-MB-231) and prostate cancer (PC-3) cell lines along with normal cell line. Several analogs were synthesized by replacing prenyl moiety with alkyl, aromatic, and heteroaromatic functionality to study the structure-activity relationship. Compounds 20 and 22 with adamantoylamino, diprenylamino and substituted benzene sulfonamide substituents showed potent antiproliferative activity in MCF-7 cell line with IC50 values of 0.48 and 0.53 μM, respectively. Both the compounds showed higher IC50 value in MCF-10A cell lines indicating nontoxicity in normal cell lines.

Generation of Dimethyl Sulfoxide Coordinated Thermally Stable Halogen Cation Pools for C?H Halogenation

A method to generate halogen cation pools from the reaction of 1,2-dihaloethanes (hal=Br, I) and dimethyl sulfoxide (DMSO) for C?H halogenation of arenes and heteroarenes was reported. The initial reaction of DMSO and 1,2-dihaloethane generates the sulfur

Electronic Finetuning of 8-Methoxy Psoralens by Palladium-Catalyzed Coupling: Acidochromicity and Solvatochromicity

Differently 5-substituted 8-methoxypsoralens can be synthesized by an efficient synthetic route with various cross-coupling methodologies, such as Suzuki, Sonogashira and Heck reaction. Compared to previously synthesized psoralens, thereby promising daylight absorbing compounds as potentially active agents against certain skin diseases can be readily accessed. Extensive investigations of all synthesized psoralen derivatives reveal fluorescence in the solid state as well as several distinctly emissive derivatives in solution. Donor-substituted psoralens exhibit remarkable photophysical properties, such as high fluorescence quantum yields and pronounced emission solvatochromicity and acidochromicity, which were scrutinized by Lippert–Mataga and Stern–Volmer plots. The results indicate that the compounds exceed the limit of visible light, a significant factor for potential applications as an active agent. In addition, (TD)DFT calculations were performed to elucidate the underlying electronic structure and to assign experimentally obtained data.