193554-93-7Relevant articles and documents
Synthesis and Antimicrobial Activity of New Dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium Salts
Tatarinov,Terekhova,Voloshina,Sapunova,Lyubina,Mironov
, p. 1800 - 1805 (2018)
New dialkyl(diaryl)-2-(5-chloro-2-hydroxyphenyl)-2-(phenylethenyl)pentylphosphonium salts bearing various substituents at the phosphorus atom were synthesized. Antimicrobial activity of the salts obtained was estimated. Derivatives with 2-methoxyphenyl substituents at the phosphorus atom are most active against grampositive bacteria. Herewith, dibenzyl-substituted phosphonium derivatives possess the best antifungal activity.
Synthesis of racemic P-chiral phosphine oxides and phosphonium salts by stepwise reaction of phosphacoumarins with organomagnesium compounds
Fayzullin, Robert R.,Kuznetsov, Denis M.,Mironov, Vladimir F.,Tatarinov, Dmitry A.
supporting information, (2020/05/14)
A new effective synthetic route to the racemic phosphine oxides and phosphonium salts with a P-asymmetric center was developed based on the stepwise reaction of phosphacoumarins with organomagnesium compounds. A selective P–C bond formation was achieved on each step owing to the differences in reactivity of the exocyclic P–Cl or P–O bonds and endocyclic P–O bond of phosphacoumarins. It was found that the P(O)OMgX fragment of the phosphocoumarin salt does not hinder in the substitution reaction at the phosphorus atom accompanied by ring-opening and P–C bond formation.
Synthesis and chemical properties of benzo[e]-1,2-oxaphosphorinine derivatives - Analogues of coumarins
Varaksina,Tatarinov,Cherkin,Nemtarev,Mironov,Konovalov
body text, p. 566 - 570 (2009/04/06)
The 4-aryl(alkyl)benzo[e]-1,2-oxaphosphorine derivatives (phosphacoumarins) were obtained by the reaction of 2,2,2-trihalogenobenzo[d]-1,3,2- dioxaphospholes with terminal acetylenes. The reactions of phosphacoumarins with halogens and Grignard reagents w