19358-42-0

Basic information

• Product Name: o-tolyl chloroformate
• Synonyms: o-tolyl chloroformate;Chloridocarbonic acid 2-methylphenyl ester;Einecs 242-993-5
• CAS NO: 19358-42-0
• Molecular Formula: C₈H₇ClO₂
• Molecular Weight: 170.59298
• EINECS: 242-993-5
• Mol File: 19358-42-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 210.9°Cat760mmHg
• Flash Point: 89.4°C
• Appearance: /
• Density: 1.234g/cm³
• Vapor Pressure: 0.187mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: o-tolyl chloroformate(CAS DataBase Reference)
• NIST Chemistry Reference: o-tolyl chloroformate(19358-42-0)
• EPA Substance Registry System: o-tolyl chloroformate(19358-42-0)

Safety Data

• Hazardous Substances Data: 19358-42-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H7ClO2/c1-6-4-2-3-5-7(6)11-8(9)10/h2-5H,1H3

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 95-48-7 ortho-cresol 
• 75-44-5 phosgene 

Downstream Products

• 18312-43-1 phenyl-carbamic acid o-tolyl ester 
• 170700-71-7 (E)-1-(hex-2-en-1-yloxy)-2-methylbenzene 
• 1419028-27-5 trans-hex-2-enyl o-tolyl carbonate 
• 888-49-3 Chlorameisensaeure-<4-nitro-2-trichlormethyl-phenylester> 
• 716-27-8 N-Methyl-carbaminsaeure-<2-trichlormethyl-phenylester> 
• 164297-03-4 C₁₈H₁₈N₂O₄S 
• 91246-84-3 O-2-methylphenyl N-isopropylcarbamate 
• 91012-03-2 ethyl-carbamic acid o-tolyl ester 
• 830-97-7 Chlorameisensaeure-<2-trichlormethyl-phenylester> 
• 58610-01-8 thiocarbonic acid S-(5-oxo-4-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl) ester O-o-tolyl ester 
• 58610-09-6 thiocarbonic acid S-(4-phenyl-5-thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-yl) ester O-o-tolyl ester 
• 38235-09-5 o-Tolyloxycarbonyylmethyldithiocarbamat 
• 38235-11-9 o-Tolyloxycarbonyldiethyldithiocarbamat 
• 38235-10-8 o-Tolyloxycarbonyldimethyldithiocarbamat 

Relevant articles and documents

Versatile Cp*Co(III)(LX) Catalyst System for Selective Intramolecular C-H Amidation Reactions

Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C-H nitrene insertion of azidoformates to afford cyclic carbamates. The cobalt complexes were easy to prepare and bench-stable, thus offering a convenient reaction protocol. The catalytic reactivity was significantly improved by the electronic tuning of the bidentate LX ligands, and the observed regioselectivity was rationalized by the conformational analysis and DFT calculations of the transition states. The superior performance of the newly developed cobalt catalyst system could be broadly applied to both C(sp2)-H and C(sp3)-H carbamation reactions under mild conditions.

AZETIDINE DERIVATIVES USEFUL FOR THE TREATMENT OF METABOLIC AND INFLAMMATORY DISEASES

Compounds are disclosed that have a formula represented by the following: These compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example inflammatory conditions, infectious diseases, autoimmune diseases, diseases involving impairment of immune cell functions, cardiometabolic diseases, and/or proliferative diseases.