193619-94-2Relevant articles and documents
Design, synthesis and anticancer screening of 3-(3-(substituted phenyl) acryloyl)-2H-chromen-2ones as selective anti-breast cancer agent
Mokale, Santosh N.,Begum, Afreen,Sakle, Nikhil S.,Shelke, Vishakha R.,Bhavale, Swati A.
, p. 966 - 972 (2017)
By utilizing concept of molecular hybridization, involving combination of various Pharmacophore, novel substituted coumarin-chalcone hybrids was synthesized and evaluated for anti-proliferative activity against estrogen receptor-positive MCF-7 and negativ
ZnS nanoparticles immobilized on graphitic carbon nitride as a recyclable and environmentally friendly catalyst for synthesis of 3-cinnamoyl coumarins
Safaei-Ghomi, Javad,Akbarzadeh, Zeinab,Teymuri, Raheleh
, p. 3425 - 3439 (2019/09/06)
Abstract: Zinc oxide nanoparticles immobilized on a graphitic carbon nitride (ZnS NPs/g-C3N4) nanocomposite were applied as an organometallic recyclable catalyst in the synthesis of coumarin–chalcone hybrids through the Claisen–Schmi
Bismuth triflate: A highly efficient catalyst for the synthesis of bio-active coumarin compounds via one-pot multi-component reaction
El-Remaily, Mahmoud. Abd El Aleem. Ali. Ali.
, p. 1124 - 1130 (2015/07/07)
A series of coumarin-chalcone hybrid compounds and coumarins linked to pyrazoline was synthesized in good yield and short time using a simple and efficient method. This method involved the one-pot reaction of salicylaldehyde, an α-ketoester and an aromatic aldehyde (in the case of the coumarin-chalcone derivatives) in addition to hydrazine hydrate (in the case of the pyrazolyl coumarins) in the presence of a catalytic amount of bismuth triflate [Bi(OTf)3, 5 mol%]. The synthesized compounds showed scavenging activity towards the free radical 2,2-diphenyl-1-picrylhydrazyl. All compounds were characterized using IR, 1H NMR and 13C NMR spectroscopy.
