193885-36-8

Basic information

• Product Name: 2-(2,3-Dihydrobenzo[b][1,4]dioxin-7-yl)propanoic acid
• CAS NO: 193885-36-8
• Molecular Weight: 208.214
• Mol File: 193885-36-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 351.5±41.0 °C(Predicted)
• Density: 1.276±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(2,3-Dihydrobenzo[b][1,4]dioxin-7-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,3-Dihydrobenzo[b][1,4]dioxin-7-yl)propanoic acid(193885-36-8)
• EPA Substance Registry System: 2-(2,3-Dihydrobenzo[b][1,4]dioxin-7-yl)propanoic acid(193885-36-8)

Safety Data

• Hazardous Substances Data: 193885-36-8(Hazardous Substances Data)

Upstream product

• 215175-90-9 Ethyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-7-yl)propanoate 
• 1026628-22-7 Toluene-4-sulfonic acid 1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethyl ester 
• 131030-47-2 2,3-dihydrobenzo[1,4]dioxin-6-ylhydroxyacetic acid ethyl ester 
• 193885-37-9 2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetic acid 
• 177158-18-8 2-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1-morpholin-4-yl-ethanethione 
• 2879-20-1 1,4-benzodioxan-6-yl methyl ketone 
• 7338-03-6 1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)ethan-1-ol 
• 493-09-4 benzo-1,4-dioxane 
• 17253-11-1 2,3-dihydro-1,4-benzodioxin-6-ylacetic acid 
• 74-88-4 methyl iodide 
• 193885-38-0 2-(R,S)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxypropanoic acid 
• 193885-35-7 2-(2,3-dihydro-1,4-benzodioxin-6-yl)propionitrile 

Relevant articles and documents

SUBSTITUTED AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted aromatic carboxamide and urea derivatives, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions (formula (I)).

Synthesis and anti-inflammatory activity of rac-2-(2,3-dihydro-1,4-benzodioxin)propionic acid and its R and S enantiomers

Racemic (R,S)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)propionic acid (3) has been prepared from 2,3-dihydro-1,4-benzodioxin. R-(-)-Pantolactone has been used as auxiliary for the synthesis of R-3 and S-3. The anti-inflammatory properties of the new carboxylic acids are described and compared with other anti-inflammatory agents. The highest activity is exhibited by compound S-3.