194152-23-3Relevant articles and documents
Nonpeptide oxytocin antagonists: Potent, orally bioavailable analogs of L-371,257 containing A 1-R-(pyridyl)ethyl ether terminus
Kuo, Michelle S.,Bock, Mark G.,Freidinger, Roger M.,Guidotti, Maribeth T.,Lis, Edward V.,Pawluczyk, Joseph M.,Perlow, Debra S.,Pettibone, Douglas J.,Quigley, Amy G.,Reiss, Duane R.,Williams, Peter D.,Woyden, Carla J.
, p. 3081 - 3086 (1998)
Structure-activity studies on the oxytocin antagonist 1 (L-371,257) have identified a new series of high affinity, receptor-selective OT antagonists in which the N-acetyl-4-piperidinyl ether terminus in 1 has been replaced with a 1-(aryl)ethoxy group.