194487-79-1

Basic information

• Product Name: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester
• Synonyms: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester;4-Bromo-2-ethyl-benzoic acid methyl ester;Methyl 4-bromo-2-ethylbenzoate
• CAS NO: 194487-79-1
• Molecular Formula: C₁₀H₁₁BrO₂
• Molecular Weight: 258.11178
• Mol File: 194487-79-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(194487-79-1)
• EPA Substance Registry System: (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester(194487-79-1)

Safety Data

• Hazardous Substances Data: 194487-79-1(Hazardous Substances Data)

Usage

Description

(S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester is a chemical compound with the molecular formula C11H13BrNO2. It is a methyl ester derivative of 2-(1-amino-ethyl)-4-bromo-benzoic acid, characterized by its white to off-white solid appearance and solubility in organic solvents. With a melting point of approximately 70-80 degrees Celsius, this compound holds potential as an intermediate for the synthesis of pharmaceuticals and other organic compounds due to its pharmacological properties.

Uses

Used in Pharmaceutical Synthesis:
(S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs and organic compounds. Its unique structure and reactivity make it a valuable building block in the development of new medications.
Used in Chemical Research:
In the field of chemical research, (S)-2-(1-Amino-ethyl)-4-bromo-benzoic acid methyl ester is utilized as a subject for studying its properties, reactivity, and potential applications in organic synthesis. This research can lead to the discovery of new compounds and materials with beneficial properties.

Upstream product

• 67-56-1 methanol 
• 2386-64-3 ethylmagnesium chloride 
• 112704-79-7 2-fluoro-4-bromobenzoic acid 
• 644984-78-1 4-bromo-2-ethylbenzoic acid 
• 74-88-4 methyl iodide 
• 68837-59-2 4-bromo-2-methylbenzoic acid 

Downstream Products

• 935260-96-1 methyl 4-cyano-2-ethylbenzoate 
• 1227090-87-0 methyl 2-(4-bromo-2-ethylphenyl)acetate 
• 855931-72-5 2-(4-bromo-2-ethylphenyl)acetic acid 
• 877131-20-9 2-(4-bromo-2-ethylphenyl)acetonitrile 
• 877131-21-0 (4-bromo-2-ethylphenyl)methanol 
• 552330-86-6 5-bromoisoindolin-1-one 

Relevant articles and documents

MACROCYCLIC COMPOUND AND USE THEREOF

A compound represented by the following formula (I): wherein each symbol in the formula is as described herein or a salt thereof has an NRF2 activating activity, and is expected to be useful as a preventive or therapeutic agent for diseases associated with oxidative stress, in particular, hepatic disease (for example, non-alcoholic steatohepatitis (NASH)), cardiovascular disease (for example, heart failure or pulmonary arterial hypertension), lung disease (for example, chronic obstructive pulmonary disease (COPD)), kidney disease (for example, chronic kidney disease (CKD) or acute kidney injury (AKI)), central nervous system disease (for example, Parkinson's disease), mitochondrial disease (for example, Friedreich motor ataxia, mitochondrial myopathy), inflammatory disease (for example, multiple sclerosis (MS), inflammatory bowel disease (IBD)), sickle cell disease, cancer, or the like.

PYRIMIDINE DERIVATIVES AS PGE2 RECEPTOR MODULATORS

The present invention relates to pyrimidine derivatives of formula (I) wherein (R1)n, R3, R4a, R4b, R5a, R5b and Ar1 are as described in the description and their use in the treatment of cancer by modulating an immune response comprising a reactivation of the immune system in the tumor. The invention further relates to novel benzofurane and benzothiophene derivatives of formula (II) and their use as pharmaceuticals, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as modulators of the prostaglandin 2 receptors EP2 and/or EP4.

HISTONE DEMETHYLASE INHIBITORS

Provided herein are substituted pyrazolylpyridine, pyrazolylpyridazine, and pyrazolylpyrimidine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.