194610-48-5

Basic information

• Product Name: N-(3,5-dimethylphenyl)-1,8-naphthalimide
• Synonyms: N-(3,5-dimethylphenyl)-1,8-naphthalimide
• CAS NO: 194610-48-5
• Molecular Weight: 301.345
• Mol File: 194610-48-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3,5-dimethylphenyl)-1,8-naphthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,5-dimethylphenyl)-1,8-naphthalimide(194610-48-5)
• EPA Substance Registry System: N-(3,5-dimethylphenyl)-1,8-naphthalimide(194610-48-5)

Safety Data

• Hazardous Substances Data: 194610-48-5(Hazardous Substances Data)

Downstream Products

• 4948-15-6 N,N'-bis(3',5'-dimethylphenyl)perylenetetracarboxylic diimide 

Relevant articles and documents

Neurotrophin antagonist compositions

A pharmaceutical composition comprising a compound of Formula I 1wherein R1 is selected from, inter alia, alkyl, aryl-loweralkyl, heterocycle-loweralkyl, loweralkyl-carbonate; optionally substituted amino; benzimidaz-2-yl; optionally substituted phenyl; loweralkyl-(R5)(R6) wherein one of R5 and R6 is selected from H and and the other is selected from carboxy, carboxy-loweralkyl and loweralkoxycarbonyl; NHCH2CH2OX wherein X represents an in vivo hydrolyzable ester; and R2 and R3 are independently selected from H, NO2, halo, di(loweralkyl)amino, cyano, C(O)OH, phenyl-S—, loweralkyl, and Z(O)OR7 wherein Z is selected from C and S and R7 is selected from H, loweralkylamino and arylamino; or pharmaceutically acceptable salts or certain in vivo hydrolyzable esters or amides thereof, in an amount effective to inhibit neurotrophin-mediated activity, and a suitable carrier, is described. The compositions are useful to inhibit undesirable neurotrophin-mediated activity such as the neurite outgrowth that occurs in some neurodegenerative disease states.