194669-41-5 Usage
Description
1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-(2-methoxyphenyl)-, 1,1-dimethylethyl ester, also known as roxithromycin, is a semi-synthetic macrolide antibiotic with the molecular formula C20H23NO3. It is a t-butyl ester derivative of 3,6-dihydro-4-(2-methoxyphenyl)-1(2H)-pyridinecarboxylic acid. Roxithromycin is characterized by its ability to inhibit bacterial protein synthesis, effectively halting their growth and replication.
Uses
Used in Pharmaceutical Industry:
1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-(2-methoxyphenyl)-, 1,1-dimethylethyl ester is used as a broad-spectrum antibiotic for treating various bacterial infections. It is particularly effective against respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases. Roxithromycin is valued for its relatively low risk of side effects and its ability to target a wide range of bacterial pathogens.
Used in Research and Development:
In the field of medical research, 1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-(2-methoxyphenyl)-, 1,1-dimethylethyl ester serves as a valuable compound for studying the mechanisms of antibiotic action and resistance. It can be used to develop new drugs or improve existing ones, potentially leading to more effective treatments for bacterial infections.
Used in Drug Delivery Systems:
Similar to gallotannin, roxithromycin can also be incorporated into novel drug delivery systems to enhance its efficacy and bioavailability. These systems may include organic and metallic nanoparticles, which can improve the delivery of the antibiotic to target sites, reducing the required dosage and minimizing potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 194669-41-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,6,6 and 9 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 194669-41:
(8*1)+(7*9)+(6*4)+(5*6)+(4*6)+(3*9)+(2*4)+(1*1)=185
185 % 10 = 5
So 194669-41-5 is a valid CAS Registry Number.
194669-41-5Relevant articles and documents
20-HETE FORMATION INHIBITORS
-
Paragraph 0257; 0258; 0271; 0272, (2020/08/23)
This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.
AROMATIC HETEROCYCLIC COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS
-
Paragraph 00331, (2015/07/07)
Provided herein are novel aromatic heterocyclic compounds or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and their uses for treating Alzheimer's disease. Also provided herein are pharmaceutical compositions containing such compounds, and methods for using such compounds or pharmaceutical compositions thereof to treat Alzheimer's disease.
Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl- cyclopropane carboxamide derivatives as novel melatonin receptor ligands
Li, Guiying,Zhou, Hao,Jiang, Yu,Keim, Holger,Topiol, Sidney W.,Poda, Suresh B.,Ren, Yong,Chandrasena, Gamini,Doller, Darío
scheme or table, p. 1236 - 1242 (2011/04/16)
Two series of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives exhibiting diverse functionality at rat MT1 and MT2 receptors are reported. Compounds 11f and 18b (MT 1/MT2 agonist) have human microsomal intrinsic clearance comparable to ramelteon.
