19473-20-2

Basic information

• Product Name: (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one
• Synonyms: (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one
• CAS NO: 19473-20-2
• Molecular Weight: 132.116
• Mol File: 19473-20-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one(19473-20-2)
• EPA Substance Registry System: (3S,5S)-(+)-3-hydroxy-5-hydroxymethyl-tetrahydrofuran-2-one(19473-20-2)

Safety Data

• Hazardous Substances Data: 19473-20-2(Hazardous Substances Data)

Upstream product

• 87-72-9 D-Xylose 
• 39823-98-8 (S)-3-benzyloxy-5-hydroxymethyl-2(5H)-furanone 

Downstream Products

• 178811-63-7 (3S,5S)-5-Benzyloxymethyl-3-methoxymethoxy-dihydro-furan-2-one 
• 178811-64-8 (2S,4S)-5-Benzyloxy-2-methoxymethoxy-pentane-1,4-diol 
• 178811-70-6 (2R,4S)-2-Benzyloxymethyl-4-methoxymethoxy-1-oxo-1λ⁵-phospholan-1-ol 
• 178811-65-9 Methanesulfonic acid (1S,3S)-1-benzyloxymethyl-4-methanesulfonyloxy-3-methoxymethoxy-butyl ester 
• 152711-17-6 (S)-3-benzyloxy-5-hydroxymethyl-2(5H)-furanone 
• 178811-62-6 (3S,5S)-5-Benzyloxymethyl-3-hydroxydihydrofuran-2(3H)-one 
• 26532-13-8 methyl 2,5-di-O-benzoyl-3-deoxy-α-D-threo-pentofuranoside 
• 162889-26-1 1α-di<(2-methoxyethoxy)methoxy>vitamin D₃ 
• 162889-21-6 (3S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(2-methoxy-ethoxymethoxy)-dihydro-furan-2-one 
• 166450-62-0 (2S,4S)-5-(tert-Butyl-diphenyl-silanyloxy)-4-hydroxy-2-(2-methoxy-ethoxymethoxy)-pentanal 
• 41294-56-8 1α-hydroxyvitamin D3 
• 152963-78-5 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose 
• 152963-76-3 (3R,5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)-3-fluorodihydrofuran-2(3H)-one 

Relevant articles and documents

Synthetic approaches to either homochiral or achiral derivatives of 3-hydroxy-2(5H)-furanone (isotetronic acid)

Several title compounds were synthesized according to new methods based either on the use of D-ribonolactone as a chiral precursor or on the cyclization of 2,4-dioxopentanoic acid as a suitable achiral precursor. Base-induced elimination and subsequent acid-promoted ring contraction is an efficient protocol for the preparation of isotetronic acids from 2-O-alkyl-3,4-O-benzylidene-D-ribono-1,5-lactone derivatives.