194736-67-9Relevant articles and documents
Zelkovamycin is an OXPHOS Inhibitory Member of the Argyrin Natural Product Family
Krahn, Daniel,Heilmann, Geronimo,Vogel, Felix C. E.,Papadopoulos, Chrisovalantis,Zweerink, Susanne,Kaschani, Farnusch,Meyer, Hemmo,Roesch, Alexander,Kaiser, Markus
, p. 8524 - 8531 (2020)
Natural products (NPs) are an important inspirational source for developing drugs and chemical probes. In 1999, the group of ōmura reported the constitutional elucidation of zelkovamycin. Although largely unrecognized so far, this NP displays structural s
Deracemization of amino acids by coupling transaminases of opposite stereoselectivity
Park, Eul-Soo,Shin, Jong-Shik
supporting information, p. 3505 - 3509 (2015/02/19)
Biocatalytic deracemization of amino acids without relying on oxidase-based deamination of an unwanted enantiomer was demonstrated by coupling a-and w-transaminases displaying opposite stereoselectivity. This strategy employs isopropylamine and a keto acid as cosubstrates and is free of generation of hydrogen peroxide which is troublesome in the conventional oxidase-based methods.