194785-18-7

Basic information

• Product Name: 6-CARBOXY-X-RHODAMINE
• Synonyms: 6-ROX;6-CARBOXY-X-RHODAMINE;6-CARBOXY-X-RHODAMINE, FOR FLUORESCENCE*;6-CARBOXY-X-RHODAMINE (SINGLE ISOMER);6-carboxy-X-rhodaMine, triethylaMMoniuM salt;6-ROX, 6-CXR;6-ROX [6-Carboxy-X-RhodaMine];1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium,9-(2,5-dicarboxyphenyl)-2,3,6,7,12,13,16,17-octahydro-, inner salt
• CAS NO: 194785-18-7
• Molecular Formula: C₃₃H₃₀N₂O₅
• Molecular Weight: 534.609
• Mol File: 194785-18-7.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: DMSO: soluble
• CAS DataBase Reference: 6-CARBOXY-X-RHODAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CARBOXY-X-RHODAMINE(194785-18-7)
• EPA Substance Registry System: 6-CARBOXY-X-RHODAMINE(194785-18-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-48/20/22-40-36/38-22
• Safety Statements: 26-36/37
• WGK Germany: 3
• F: 8
• Hazardous Substances Data: 194785-18-7(Hazardous Substances Data)

Usage

Description

6-Carboxy-X-Rhodamine is a single isomer, long wavelength rhodamine-based dye known for its unique fluorescent properties. It is characterized by its ability to emit light at specific wavelengths when excited, making it a versatile compound for various applications across different industries.

Uses

Used in Research and Diagnostics:
6-Carboxy-X-Rhodamine is used as a tracer agent for tracking and visualizing the movement, distribution, and localization of molecules or cells within biological systems. Its fluorescent properties allow for easy detection and monitoring, making it a valuable tool in research and diagnostics.
Used in Medical Applications:
In the medical field, 6-Carboxy-X-Rhodamine is used as a labeling agent for biologics, such as proteins, antibodies, and nucleic acids. This enables the identification, quantification, and study of these biomolecules, contributing to the development of new drugs and therapies.
Used in Laser Technology:
6-Carboxy-X-Rhodamine is also utilized as a laser dye in various laser applications due to its ability to efficiently convert light energy into specific wavelengths. This makes it suitable for use in laser systems that require precise control over the emitted light, such as in medical procedures, scientific research, and industrial processes.
Used in Analytical Chemistry:
In analytical chemistry, 6-Carboxy-X-Rhodamine serves as a valuable tool for the detection and quantification of specific substances. Its fluorescent properties allow for sensitive and selective detection, making it an essential component in the development of new analytical methods and techniques.
Used in Material Science:
6-Carboxy-X-Rhodamine is employed in the development of advanced materials with specific optical properties. Its ability to emit light at specific wavelengths makes it a useful component in the creation of materials for applications such as optical sensors, display technologies, and photovoltaic devices.
Used in Environmental Monitoring:
In environmental monitoring, 6-Carboxy-X-Rhodamine is used as a tracer to study the behavior and fate of pollutants in the environment. Its fluorescent properties enable the detection and tracking of contaminants, helping to assess their impact on ecosystems and inform strategies for pollution control and remediation.

InChI:InChI=1/C33H30N2O5/c36-32(37)20-9-10-21(33(38)39)24(17-20)27-25-15-18-5-1-11-34-13-3-7-22(28(18)34)30(25)40-31-23-8-4-14-35-12-2-6-19(29(23)35)16-26(27)31/h9-10,15-17H,1-8,11-14H2,(H-,36,37,38,39)

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Relevant articles and documents

Preparation process of carboxyl-X-rhodamine

The invention provides a preparation process of carboxyl-X-rhodamine, which adopts 8-hydroxyjulolidine phenol and trimellitic anhydride as raw materials, an intermediate 5, 6-carboxyl-X-rhodamine is synthesized by a direct cyclization method, a high-boiling-point solvent is adopted as a cyclization medium, and a cyclization product has poor solubility in the solvent and can be precipitated in a reaction system, so that the yield of 5, 6-carboxyl-X-rhodamine is increased, and the yield of 5, 6-carboxyl-X-rhodamine is increased. Therefore, the reaction conversion rate and the purification simplicity are obviously improved; 5, 6-carboxyl-X-rhodamine and organic amine are salified, so that the separation cost is greatly reduced, the operation steps are simplified, and the industrial production of carboxyl-X-rhodamine becomes possible; an acid precipitation method is adopted, the 5-carboxyl-X-rhodamine ammonium salt and the 6-carboxyl-X-rhodamine ammonium salt are converted into the 5-carboxyl-X-rhodamine and the 6-carboxyl-X-rhodamine, and the efficiency is high; the whole preparation process has the advantages of simplicity and convenience in operation, low equipment requirement, low cost, high equipment use efficiency and the like, and meets the requirements of industrial production and application.

CELL-PENETRATING FLUORESCENT DYES WITH SECONDARY ALCOHOL FUNCTIONALITIES

The invention relates to novel cell-penetrating fluorescent dyes with with secondary alcohol functionalities having one of the following general formulae I-III and 4: The invention also relates to the use of these compounds for optical microscopy and imaging techniques.

METHODS FOR SYNTHESIZING RHODAMINE DYES

Described herein are methods for the regioselective synthesis of substituted rhodamine dyes.