194853-86-6 Usage
Description
4-Fluoro-2-trifluoromethylbenzonitrile is an organic compound characterized by its white solid appearance. It is a derivative of benzonitrile with a fluorine atom at the 4th position and a trifluoromethyl group at the 2nd position. 4-Fluoro-2-trifluoromethylbenzonitrile is known for its unique chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
4-Fluoro-2-trifluoromethylbenzonitrile is used as a pharmaceutical intermediate for the development of various drugs. Its unique chemical structure allows it to serve as a building block in the synthesis of complex molecules with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-Fluoro-2-trifluoromethylbenzonitrile is utilized for the synthesis of diphenylthioethers. These compounds have a wide range of applications, including their use as additives, stabilizers, and intermediates in the production of various chemicals and materials.
Overall, 4-Fluoro-2-trifluoromethylbenzonitrile is a versatile compound with significant potential in both the pharmaceutical and chemical synthesis industries. Its unique properties and applications make it an important compound for researchers and chemists working in these fields.
Check Digit Verification of cas no
The CAS Registry Mumber 194853-86-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,8,5 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 194853-86:
(8*1)+(7*9)+(6*4)+(5*8)+(4*5)+(3*3)+(2*8)+(1*6)=186
186 % 10 = 6
So 194853-86-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H3F4N/c9-6-2-1-5(4-13)7(3-6)8(10,11)12/h1-3H
194853-86-6Relevant articles and documents
Rhodium-catalyzed transformation of heteroaryl aryl ethers into heteroaryl fluorides
Arisawa, Mieko,Tanii, Saori,Tazawa, Takeru,Yamaguchi, Masahiko
supporting information, p. 11390 - 11393 (2016/09/23)
A rhodium complex catalyzed the conversion of the C-O bond of heteroaryl aryl ethers to the C-F bond. The reaction of (4-chlorophenylthio)pentafluorobenzene with heteroaryl aryl ethers provided heteroaryl fluorides and heteroaryl (4-chlorophenylthio)tetrafluorophenyl ethers; this involved the cleavage of a single heteroaryl C-O bond under equilibrium conditions. The reaction of heteroaryl aryl ethers with 2-fluorobenzothiazole in which two heteroaryl and aryl C-O bonds were cleaved provided heteroaryl fluorides and aryl fluorides. The reactions were applicable to five-membered and six-membered heteroaryl aryl ethers and also to diaryl ethers possessing one or two electron-withdrawing groups.