194869-21-1

Basic information

• Product Name: Carbamic acid, [4-methoxy-2-[(trimethylsilyl)ethynyl]phenyl]-, 1,1-dimethylethyl ester
• CAS NO: 194869-21-1
• Molecular Formula: C17H25NO3Si
• Molecular Weight: 319.476
• Mol File: 194869-21-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [4-methoxy-2-[(trimethylsilyl)ethynyl]phenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [4-methoxy-2-[(trimethylsilyl)ethynyl]phenyl]-, 1,1-dimethylethyl ester(194869-21-1)
• EPA Substance Registry System: Carbamic acid, [4-methoxy-2-[(trimethylsilyl)ethynyl]phenyl]-, 1,1-dimethylethyl ester(194869-21-1)

Safety Data

• Hazardous Substances Data: 194869-21-1(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 18437-68-8 tert-butyl N-(4-methoxyphenyl)carbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 157496-75-8 tert-butyl (2-iodo-4-methoxyphenyl)carbamate 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1006-94-6 5-methoxylindole 

Relevant articles and documents

General and facile synthesis of indoles with oxygen-bearing substituents at the benzene moiety

Indoles with oxygen-bearing substituents such as a methoxy or (triisopropylsilyl)oxy group at all of the positions of the benzene moiety were synthesized by cyclization of tert-butyl methoxy(or (triisopropylsilyl)oxy)-2-((trimethylsilyl)ethynyl)phenyl)carbamates with potassium tert-butoxide in tert-butyl alcohol. The (ethynylphenyl)carbamates were synthesized by the palladium-catalyzed reaction of (trimethylsilyl)acetylene and the corresponding (iodophenyl)carbamates, which were selectively synthesized by directed lithiation of the phenylcarbamates and subsequent iodination.