194980-11-5Relevant articles and documents
Small molecules as structural and functional mimics of sialyl Lewis X tetrasaccharide in selectin inhibition: A remarkable enhancement of inhibition by additional negative charge and/or hydrophobic group
Wong, Chi-Huey,Moris-Varas, Francisco,Hung, Shang-Cheng,Marron, Thomas G.,Lin, Chun-Cheng,Gong, Ke Wei,Weitz-Schmidt, Gabriele
, p. 8152 - 8158 (2007/10/03)
Several sialyl Lewis X (SLe(X))) mimics that contain the essential functional groups for receptor interaction and a negative charge or a hydrophobic group have been developed as inhibitors of E-, P-, and L-selectins. Some of the mimics exhibit selectin in