195323-89-8

Basic information

• Product Name: Benzenemethanol, 2-[(2-propenyloxy)methyl]-
• CAS NO: 195323-89-8
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 195323-89-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-[(2-propenyloxy)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-[(2-propenyloxy)methyl]-(195323-89-8)
• EPA Substance Registry System: Benzenemethanol, 2-[(2-propenyloxy)methyl]-(195323-89-8)

Safety Data

• Hazardous Substances Data: 195323-89-8(Hazardous Substances Data)

Usage

General Description

Benzenemethanol, 2-[(2-propenyloxy)methyl]- is a chemical compound with a molecular formula C11H14O2. It is also known as allylphenylcarbinol and is classified as an allyl ether. This chemical is commonly used as a fragrance and flavor additive in various products such as perfumes, cosmetics, and food items. It is also used in the production of pharmaceuticals and as a solvent in chemical processes. Benzenemethanol, 2-[(2-propenyloxy)methyl]- is considered to have low toxicity and is generally regarded as safe for use in these applications. However, proper handling and storage procedures should be followed to ensure safety.

Upstream product

• 81168-17-4 2-(tert-butyldimethylsiloxymethyl)benzyl alcohol 
• 612-14-6 phthalyl alcohol 
• 107-05-1 3-chloroprop-1-ene 
• 106-95-6 allyl bromide 

Downstream Products

• 625445-24-1 1-allyloxymethyl-2-bromomethylbenzene 
• 181183-82-4 2-(2-propen-1-yloxymethyl)benzyl diazoacetate 
• 873300-24-4 o-(allyloxymethyl)benzaldehyde 

Relevant articles and documents

Influence of the -CH2X substituent on the regioselectivity of intramolecular meta -photocycloaddition reactions

In studies related to the synthesis of the bicyclo[3.2.1]octane core of enterocin by an intramolecular meta-photocycloaddition, it was found that the regioselectivity of the reaction depends strongly on the substituent -CH2X in the ortho-positi

Macrocycle formation by catalytic intramolecular cyclopropanation. A new general methodology for the synthesis of macrolides

Catalytic intramolecular cyclopropanation by diazoacetates onto a remote carbon-carbon double bond resulting in the formation of 9- to 20-membered ring lactones is reported. When competition exists between proximal allylic and remote olefinic cyclopropanation, macrocyclization is favored by catalysts of increasing electrophilicity: Rh2(pfb)4 > Rh2(OAc)4, Cu(MeCN)4PF6 > Rh(cap)4, and Cu(acac)2. Terpene systems, cis-nerolidyl diazoacetate and related structures, malonic ester derivatives, and those with 1,2-benzenedimethanol, pentaerythritol, and cis-2-buten-1, 4-diol linkers undergo cyclopropanation onto the most remote carbon-carbon double bond in good yield. Generally, only one cyclopropane diastereoisomer is observed but increasing ring size allows stereochemistries in macrocyclization reactions that resemble those of their intermolecular cyclopropanation counterparts, In one system (25) macrocyclic addition is accompanied by ylide formation/[2,3]-sigmatropic rearrangement resulting in the formation of a 10-membered ring lactone. Overall, few limits to macrocycle formation are evident, and the methodology appears to have general applicability.